Randomized Placebo Controlled Study of Ciclesonide in Preschool Children with Recurrent Wheeze and a Positive Asthma Predictive Index or Atopy

Paediatrics in Amsterdam

“…Ciclesonide has recently been approved for children o12 yrs of age in many countries, and being a pro-drug has a proposed beneficial effect to sideeffect ratio, with demonstrated effects on asthma control in adults [50]. In line with the latter study, in a large multicentre study in preschool children, BRAND et al [51] found a modest reduction of exacerbation rates and improved lung function with ciclesonide.…”