2024
DOI: 10.1101/2024.09.30.615781
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RAPDOR: Using Jensen-Shannon Distance for the computational analysis of complex proteomics datasets

Luisa Hemm,
Dominik Rabsch,
Halie R. Ropp
et al.

Abstract: The computational analysis of large proteomics datasets, such as those from gradient profiling or spatially resolved proteomics, is often as crucial as the experimental design. We present RAPDOR, a tool for intuitive analyzing and visualizing such datasets, based on the Jensen-Shannon distance and subsequent analysis of similarities between replicates, applied to three datasets. First, we examined the in-gradient distribution profiles of protein complexes with or without RNase treatment (GradR) to identify the… Show more

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