Rapid and label-free detection of COVID-19 using coherent anti-Stokes Raman scattering microscopy

Tabish, Tanveer A.; Narayan, Roger J.; Edirisinghe, Mohan

doi:10.1557/mrc.2020.81

Cited by 14 publications

(11 citation statements)

References 60 publications

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“…Nanotechnology is a highly complex but promising concept that has already been widely adapted against COVID-19 since the SARS-CoV-2 virus and nanotechnological tools operate on a similar size scale [97]. Understanding, altering and controlling those interactions can help researchers to develop rapid and more accurate virus detection implementations and better control tools as well as more effective PPE [98][99][100].…”

Section: Nanotechnological Approaches Against Covid-19mentioning

confidence: 99%

Surface interactions and viability of coronaviruses

Aydoğdu

Altun

Chung

et al. 2021

J. R. Soc. Interface.

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The recently emerged coronavirus pandemic (COVID-19) has become a worldwide threat affecting millions of people, causing respiratory system related problems that can end up with extremely serious consequences. As the infection rate rises significantly and this is followed by a dramatic increase in mortality, the whole world is struggling to accommodate change and is trying to adapt to new conditions. While a significant amount of effort is focused on developing a vaccine in order to make a game-changing anti-COVID-19 breakthrough, novel coronavirus (SARS-CoV-2) is also developing mutations rapidly as it transmits just like any other virus and there is always a substantial chance of the invented antibodies becoming ineffective as a function of time, thus failing to inhibit virus-to-cell binding efficiency as the spiked protein keeps evolving. Hence, controlling the transmission of the virus is crucial. Therefore, this review summarizes the viability of coronaviruses on inanimate surfaces under different conditions while addressing the current state of known chemical disinfectants for deactivation of the coronaviruses. The review attempts to bring together a wide spectrum of surface–virus–cleaning agent interactions to help identify material selection for inanimate surfaces that have frequent human contact and cleaning procedures for effective prevention of COVID-19 transmission.

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Section: Nanotechnological Approaches Against Covid-19mentioning

confidence: 99%

Surface interactions and viability of coronaviruses

Aydoğdu

Altun

Chung

et al. 2021

J. R. Soc. Interface.

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“…[ 78 ] The ultrasensitive and specific potential for biomarker detection with Raman spectroscopy has piqued interest for the detection of SARS‐CoV‐2. [ 79,80 ] SERS can distinguish between viruses, viral strains, and viruses with gene deletions in biological medium based on their spectral differences, [ 81 ] it is a potent advantage and opportunity for tattoo functionalization.…”

Section: Technologicals For Tattoo Optical Biosensorsmentioning

confidence: 99%

Tattoo Inks for Optical Biosensing in Interstitial Fluid

Pazos

Elani

et al. 2021

Adv Healthcare Materials

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The persistence of traditional tattoo inks presents an advantage for continuous and long‐term health monitoring in point of care devices. The replacement of tattoo pigments with optical biosensors aims a promising alternative for monitoring blood biomarkers. Tattoo inks functionalization enables the control of interstitial biomarkers with correlated concentrations in plasma, to diagnose diseases, evaluate progression, and prevent complications associated with physio pathological disorders or medication mismatches. The specific biomarkers in interstitial fluid provide a new source of information, especially for skin diseases. The study of tattoo inks displays insufficient regulation in their composition, a lack of reports of the related complications, and a need for further studies on their degradation kinetics. This review focuses on tattoo optical biosensors for monitoring dermal interstitial biomarkers and discusses the clinical advantages and main challenges for in vivo implantation. Tattoo functionalization provides a minimally invasive, reversible, biocompatible, real‐time sensing with long‐term permanence and multiplexing capabilities for the control, diagnosis, and prevention of illness; it enables self‐controlling management by the patient, but also the possibility of sending the records to the doctor.

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“…One of these is to have a good understanding in surface interactions and viability of coronaviruses, especially in relation to inanimate surfaces and cleaning protocols [ 4 ]. The second is in the innovation of novel methods to detect Covid-19 [ 1 , 25 ]. In pursuing these key lines of intervention, we can truly help defeat Covid-19 and any subsequent outbreaks, as soon as possible.…”

Section: Resultsmentioning

confidence: 99%

Perspective: Covid-19; emerging strategies and material technologies

et al. 2021

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It will be remembered in history as the event that brought the world together with science and technology; the COVID-19 pandemic has allowed for decades worth of progression in both healthcare policies and technology development. It has been a show of unprecedented global health policies ranging from the legal requirement for public facemask use to the use of tough movement restrictions that has bought the world’s economy to its knees. Here, we observe the impact of national lockdowns, facemask usage, and their effect on infection rates. It is clear that healthcare policies alone cannot tackle a pandemic. There is a huge pressure to develop personal protective equipment that not only has the capacity to prevent transmission but also has the ergonomics to be worn for long durations. In this work, we reveal our views and thoughts on the healthcare policies and developing materials and technology strategies that have contributed to reduce the damage of the pandemic, coming from the perspectives of materials scientists and a UK National Health Service consultant doctor.

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Rapid and label-free detection of COVID-19 using coherent anti-Stokes Raman scattering microscopy

Cited by 14 publications

References 60 publications

Surface interactions and viability of coronaviruses

Surface interactions and viability of coronaviruses

Tattoo Inks for Optical Biosensing in Interstitial Fluid

Perspective: Covid-19; emerging strategies and material technologies

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