Rapid and progressive decline despite early intervention in a case of bilateral hemorrhagic occlusive retinal vasculitis

Motlagh, Mahsaw; Javid, Cameron

doi:10.1016/j.ajoc.2020.100595

Cited by 5 publications

(5 citation statements)

References 17 publications

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“… 9 There are also several reports hemorrhagic occlusive retinal vasculitis (HORV) after uncomplicated cataract surgery with prophylactic intracameral vancomycin. 14 , 15 , 16 , 17 HORV often presents with macular ischemia, sectoral retinal hemorrhage along venules, as well as retinal vasculitis and arterial occlusion. 14 The postulated mechanism of injury in HORV is thought to be a hypersensitivity or drug-mediated reaction.…”

Section: Discussionmentioning

confidence: 99%

Idiopathic retinal arterial occlusive vasculitis in the setting of multiple arterial occlusions

Wang

Chin

Almeida³

2021

American Journal of Ophthalmology Case Reports

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Purpose We present a patient with vaso-occlusive retinal vasculitis to summarize this uncommon entity and review the clinical features and management challenges applicable to patients with retinal vasculitis. Observations A 76-year-old male presented with sudden-onset severe central vision loss. On examination, vitreous hemorrhage, neovascularization of the optic nerve, peripheral segmental periphlebitis, vessel sclerosis, vascular sheathing, and retinal hemorrhages were observed, and a diagnosis of active vaso-occlusive retinal vasculitis was made. The patient then underwent a complete infectious, inflammatory, and neoplastic workup which returned negative. The patient was treated with locally with a sub-Tenon's injection of 40 mg triamcinolone on presentation and later with oral prednisone. At three-month follow-up, vision improved to 20/300 with regressing neovascularization and clearing of vitreous hemorrhage in the right eye (OD). Conclusions Considering novel associations of occlusive retinal vasculitis, it is important to recognize that idiopathic occlusive retinal vasculitis, although uncommon, can occur and represents a prototypical disease form. It is imperative that these patients have a complete infectious, inflammatory, and neoplastic workup owing to the possible overlap of masquerade clinical signs and symptoms.

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Section: Discussionmentioning

confidence: 99%

Idiopathic retinal arterial occlusive vasculitis in the setting of multiple arterial occlusions

Wang

Chin

Almeida³

2021

American Journal of Ophthalmology Case Reports

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“…Early detection, corticosteroid, and anti-VEGF treatment may improve visual outcomes in select cases 317,321–324. Patients should also be monitored for the development of subsequent neovascular glaucoma.…”

Section: Vascular Relatedmentioning

confidence: 99%

“…[313][314][315][316] Many bilateral cases have been described due to the delay in the development of occlusive vasculitis, especially in cases where both eyes are operated on in a close time frame. 317 Though some mild cases have been seen, the majority seem to have devastating visual consequences despite aggressive treatment with high-dose corticosteroids, anti-VEGF injections, antiviral medication, and pars plana vitrectomy. [318][319][320]…”

Section: Symptomsmentioning

confidence: 99%

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The Impact of Systemic Medications on Retinal Function

Somisetty

Santina

Sarraf

et al. 2023

Asia-Pacific Journal of Ophthalmology

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This study will provide a thorough review of systemic (and select intravitreal) medications, along with illicit drugs that are capable of causing various patterns of retinal toxicity. The diagnosis is established by taking a thorough medication and drug history, and then by pattern recognition of the clinical retinal changes and multimodal imaging features. Examples of all of these types of toxicity will be thoroughly reviewed, including agents that cause retinal pigment epithelial disruption (hydroxychloroquine, thioridazine, pentosan polysulfate sodium, dideoxyinosine), retinal vascular occlusion (quinine, oral contraceptives), cystoid macular edema/retinal edema (nicotinic acid, sulfa-containing medications, taxels, glitazones), crystalline deposition (tamoxifen, canthaxanthin, methoxyflurane), uveitis, miscellaneous, and subjective visual symptoms (digoxin, sildenafil). The impact of newer chemotherapeutics and immunotherapeutics (tyrosine kinase inhibitor, mitogen-activated protein kinase kinase, checkpoint, anaplastic lymphoma kinase, extracellular signal-regulated kinase inhibitors, and others), will also be thoroughly reviewed. The mechanism of action will be explored in detail when known. When applicable, preventive measures will be discussed, and treatment will be reviewed. Illicit drugs (cannabinoids, cocaine, heroin, methamphetamine, alkyl nitrite), will also be reviewed in terms of the potential impact on retinal function.

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“…Prophylactic administration of intravitreal antibiotics at the time of primary repair in eyes with high-risk characteristics has been reported to reduce the risk of posttraumatic endophthalmitis [7] . However, intravitreal vancomycin can cause hemorrhagic occlusive retinal vasculitis, resulting in severe vision loss, and the rates of endophthalmitis may be affected by techniques for administering intravitreal antibiotics [9][10][11] . Early therapeutic PPV and IOFB removal may achieve better visual outcomes [12] .…”

mentioning

confidence: 99%

Acute Bacillus cereus endophthalmitis caused by ocular perforation injury and occult intravitreal cilium implantation: a case report

Zhang,

2024

Int J Ophthalmol

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W e present a case of acute Bacillus cereus (B. cereus) endophthalmitis in a patient with an intraocular perforation injury combined with occult intravitreal cilium implantation. B. cereus endophthalmitis is a severe intraocular infection commonly caused by post-traumatic injuries. It often leads to significant vision loss or even eye loss within 12-48h [1] . The presence of an intraocular foreign body (IOFB) increases the risk of infection, while early surgical removal of IOFBs can prevent endophthalmitis, some IOFBs are difficult to detect preoperatively. The Medical Ethics Review Board of West China Hospital of Sichuan University waived application for a clinical study because this was a retrospective report of a single patient based on imaging and because no human experimentation was involved. The patient provided written informed consent to use the imaging data for publication. Case Report A 52-year-old male presented to the Ophthalmology Department with a wire wound to his left eye. About 1h earlier, the patient had pulled a coiled wire, which bounced and entered his left eye. He experienced immediate pain and blurred vision, but no bleeding. He had no history of ocular surgery or trauma. Best-corrected visual acuity was

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Rapid and progressive decline despite early intervention in a case of bilateral hemorrhagic occlusive retinal vasculitis

Cited by 5 publications

References 17 publications

Idiopathic retinal arterial occlusive vasculitis in the setting of multiple arterial occlusions

Idiopathic retinal arterial occlusive vasculitis in the setting of multiple arterial occlusions

The Impact of Systemic Medications on Retinal Function

Acute Bacillus cereus endophthalmitis caused by ocular perforation injury and occult intravitreal cilium implantation: a case report

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