Rapid Biosynthesis of AgNPs Using Soil Bacterium Azotobacter vinelandii With Promising Antioxidant and Antibacterial Activities for Biomedical Applications

Karunakaran, Gopalu; Jagathambal, Matheswaran; Gusev, Alexander; Torres, J. Antonio; Kolesnikov, Еvgeny; Кузнецов, Денис

doi:10.1007/s11837-016-2175-8

Cited by 27 publications

(15 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The functional groups are methylene, aromatic, ether, and dimeric groups. Bands at 1088 and 883 cm −1 confirm the presence of a C–N aliphatic group and a C–H aromatic group . The FTIR spectra give a clear understanding about the phytocompounds involved in the transformation of zinc acetate into ZnO NRs.…”

Section: Resultsmentioning

confidence: 88%

See 1 more Smart Citation

Eco‐friendly synthesis of ZnO nanorods using Cycas pschannae plant extract with excellent photocatalytic, antioxidant, and anticancer nanomedicine for lung cancer treatment

Sudha¹,

Ali²,

Karunakaran

et al. 2020

Applied Organom Chemis

Self Cite

View full text Add to dashboard Cite

The tunable ZnO nanorods (NRs) are produced due to the phytochemicals present in Cycas pschannae leaves which act as reducing and stabilizing agents. The confirmations of the ZnO NRs were validated using different characterization techniques: X‐ray diffraction, Fourier transform infrared spectroscopy, Brunauer, Emmett and Teller (BET), scanning electron microscopy–Energy Dispersive X‐Ray Analysis (EDX), UV–visible spectroscopy, Raman spectroscopy, and transmission electron microscopy. The ZnO NRs show unique surface area and low particle size. Photocatalytic activity was measured and found to be 50.75% at low concentrations and 78.33% at high concentrations. The antioxidant activity of the ZnO NRs also showed promising results for their use in free radical scavenging. In vitro toxicity studies using zebrafish embryos was performed to evaluate the toxic nature of it and the obtained result confirmed its non‐toxic nature. In addition, ZnO anticancer potential was verified using the A549 lung cancer cell line. Cytotoxic assessments of ZnO NRs were performed via 2,3‐bis‐(2‐methoxy‐4‐nitro‐5‐sulfophenyl)‐2H‐tetrazolium‐5‐carboxanilide (XTT), 3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyl tetrazolium bromide (MTT), and neutral red uptake assays to examine the cell death cycle on the A549 lung cancer cell. Dose‐dependent apoptosis and necrosis were confirmed by Lactate dehydrogenase (LDH) assay. It was also confirmed that ZnO NRs induce Reactive oxygen species (ROS) and apoptosis inside cancer (A549) cells via different intrinsic gene expression. Thus, based on this research it is evident that an effective ecofriendly, nontoxic potential anticancer drug can be synthesized using C. pschannae leaf extract.

show abstract

Section: Resultsmentioning

confidence: 88%

“…To overcome these problems, use of the green synthesis approach has become a hot topic of research in recent years . Green synthesis uses bio‐based materials, such as fungi, bacteria, and plants . Plants are the cheapest and most abundant in nature of these options and can easily be utilized for large‐scale production of nanoparticles.…”

Section: Introductionmentioning

confidence: 99%

Eco‐friendly synthesis of ZnO nanorods using Cycas pschannae plant extract with excellent photocatalytic, antioxidant, and anticancer nanomedicine for lung cancer treatment

Sudha¹,

Ali²,

Karunakaran

et al. 2020

Applied Organom Chemis

Self Cite

View full text Add to dashboard Cite

show abstract

“…Cadmium sulphide nanoparticles have been synthesised using bacteria in 10-20 min [120]. Various other studies have also shown rapid biogenic synthesis of nanoparticles [121][122][123][124][125].…”

Section: Discussionmentioning

confidence: 99%

“…Additionally, substantial effort is required to enhance the ability to regulate particle size and morphology, and to fine tune particle size distribution. For this reason, many biogenic studies have focused on developing methods that can result in monodisperse synthesis of nanoparticles [121]. The morphology of nanoparticles can be affected either by altering the process parameters to understand the optimal synthesis parameters.…”

Section: Discussionmentioning

confidence: 99%

Biogenic Nanoparticles: Synthesis, Characterisation and Applications

et al. 2021

View full text Add to dashboard Cite

Nanotechnology plays a big part in our modern daily lives, ranging from the biomedical sector to the energy sector. There are different physicochemical and biological methods to synthesise nanoparticles towards multiple applications. Biogenic production of nanoparticles through the utilisation of microorganisms provides great advantages over other techniques and is increasingly being explored. This review examines the process of the biogenic synthesis of nanoparticles mediated by microorganisms such as bacteria, fungi and algae, and their applications. Microorganisms offer a disparate environment for nanoparticle synthesis. Optimum production and minimum time to obtain the desired size and shape, to improve the stability of nanoparticles and to optimise specific microorganisms for specific applications are the challenges to address, however. Numerous applications of biogenic nanoparticles in medicine, environment, drug delivery and biochemical sensors are discussed.

show abstract

“…They showed a promising result in the field of cancer therapy. [ 3,4 ]…”

Section: Introductionmentioning

confidence: 99%

Novel Leea grandifolia leaves mediated synthesis of ZnO nanorods for photocatalytic and anticancer applications

Ali¹,

Sudha²,

Karunakaran

et al. 2021

Applied Organom Chemis

Self Cite

View full text Add to dashboard Cite

The main goal of this study was to use a green‐mediated approach for obtaining ZnO nanorods (NRs) using the Leea grandifolia leaf extract. The obtained ZnO NRs were studied using standard methods such as X‐ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy with energy‐dispersive X‐ray analysis, Brunauer–Emmett–Teller, and transmission electron microscopy (TEM), and the results revealed a smaller particle size with a high surface area. The scanning electron microscopy and TEM results showed that the obtained particles were having rod‐like morphology with size ranging from ~20 to ~200 nm. The results of the antioxidant and photocatalytic studies showed excellent photodegradation and free radical scavenging. The results of the in vitro toxicological study revealed that the obtained particles were nontoxic to organisms. The cytotoxicity and genotoxicity assessments concluded that the NR‐treated MCF‐7 had gone through necrosis and apoptosis. The ZnO NRs revealed excellent antibacterial activity towards various pathogens. It was clear that the green‐mediated method could be considered as a better one for the synthesis of ZnO NRs as it imparts excellent anticancer, antibacterial, and photocatalytic properties.

show abstract

Rapid Biosynthesis of AgNPs Using Soil Bacterium Azotobacter vinelandii With Promising Antioxidant and Antibacterial Activities for Biomedical Applications

Cited by 27 publications

References 31 publications

Eco‐friendly synthesis of ZnO nanorods using Cycas pschannae plant extract with excellent photocatalytic, antioxidant, and anticancer nanomedicine for lung cancer treatment

Eco‐friendly synthesis of ZnO nanorods using Cycas pschannae plant extract with excellent photocatalytic, antioxidant, and anticancer nanomedicine for lung cancer treatment

Biogenic Nanoparticles: Synthesis, Characterisation and Applications

Novel Leea grandifolia leaves mediated synthesis of ZnO nanorods for photocatalytic and anticancer applications

Contact Info

Product

Resources

About