Rapid scanning catheterscope for expanded forward-view volumetric imaging with optical coherence tomography

Lurie, Kristen L.; Gurjarpadhye, Abhijit Achyut; Seibel, Eric J.; Ellerbee, Audrey K.

doi:10.1364/ol.40.003165

Cited by 20 publications

(25 citation statements)

References 21 publications

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“…The proposed method could be miniaturized into an endoscope with a diameter as small as 1 mm. 45 The clinical potential of the combination of OCT and HSI arises from both modalities bringing complementary views of the sample: the first one giving access to sample morphology and the second to sample molecular composition. Their combination in a clinical setting could improve current diagnostic practice.…”

Section: Resultsmentioning

confidence: 99%

Combined optical coherence tomography and hyperspectral imaging using a double-clad fiber coupler

et al. 2016

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, "Combined optical coherence tomography and hyperspectral imaging using a double-clad fiber coupler," J. Biomed. Opt. 21 (11) Abstract. This work demonstrates the combination of optical coherence tomography (OCT) and hyperspectral imaging (HSI) using a double-clad optical fiber coupler. The single-mode core of the fiber is used for OCT imaging, while the inner cladding of the double-clad fiber provides an efficient way to capture the reflectance spectrum of the sample. The combination of both methods enables three-dimensional acquisition of the sample morphology with OCT, enhanced with complementary molecular information contained in the hyperspectral image. The HSI data can be used to highlight the presence of specific molecules with characteristic absorption peaks or to produce true color images overlaid on the OCT volume for improved tissue identification by the clinician. Such a system could be implemented in a number of clinical endoscopic applications and could improve the current practice in tissue characterization, diagnosis, and surgical guidance. © The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.

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Section: Resultsmentioning

confidence: 99%

Combined optical coherence tomography and hyperspectral imaging using a double-clad fiber coupler

et al. 2016

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“…A side-viewing catheter with an ultrafast micromotor scanner was used for intravascular OCT imaging at 3 MHz, using an FDML laser [129]. Recently, a forward-viewing catheter with small outer diameter was demonstrated at 2 kHz frame rate [130].…”

Section: Scanners For High-speed Octmentioning

confidence: 99%

High-speed OCT light sources and systems [Invited]

Klein¹,

Huber²

2017

Biomed. Opt. Express

202

111

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Abstract:Imaging speed is one of the most important parameters that define the performance of optical coherence tomography (OCT) systems. During the last two decades, OCT speed has increased by over three orders of magnitude. New developments in wavelength-swept lasers have repeatedly been crucial for this development. In this review, we discuss the historical evolution and current state of the art of high-speed OCT systems, with focus on wavelength swept light sources and swept source OCT systems. 3067-3086 (2012). 7. J. Xu, X. Wei, L. Yu, C. Zhang, J. Xu, K. K. Y. Wong, and K. K. Tsia, "High-performance multi-megahertz optical coherence tomography based on amplified optical time-stretch," Biomed. Opt. Express 6(4), 1340-1350 (2015). 8. D. J. Fechtig, B. Grajciar, T. Schmoll, C. Blatter, R. M. Werkmeister, W. Drexler, and R. A. Leitgeb, "Line-field parallel swept source MHz OCT for structural and functional retinal imaging," Biomed. Opt. Express 6(3), 716-735 (2015). 9. T. Klein, W. Wieser, L. Reznicek, A. Neubauer, A. Kampik, and R. Huber, "Multi-MHz retinal OCT," Biomed.Opt. Express 4(10), 1890-1908 (2013). 10. E. A. Swanson, D. Huang, M. R. Hee, J. G. Fujimoto, C. P. Lin, and C. A. Puliafito, "High-speed optical coherence domain reflectometry," Opt. Lett. 17(2), 151-153 (1992). 11. G. J. Tearney, B. E. Bouma, S. A. Boppart, B. Golubovic, E. A. Swanson, and J. G. Fujimoto, "Rapid acquisition of in vivo biological images by use of optical coherence tomography," Opt. Lett. 21(17), 1408-1410 (1996). 12. G. J. Tearney, B. E. Bouma, and J. G. Fujimoto, "High-speed phase-and group-delay scanning with a gratingbased phase control delay line," Opt. Lett. 22(23), 1811-1813 (1997). 13. A. Rollins, S. Yazdanfar, M. Kulkarni, R. Ung-Arunyawee, and J. Izatt, "In vivo video rate optical coherence tomography," Opt. Express 3(6), 219-229 (1998). 14. G. Häusler and M. W. Lindner, "Coherence radar and 'spectral radar'-new tools for dermatological diagnosis," J.Biomed. Opt. 3(1), 21-31 (1998). 15. B. Golubovic, B. E. Bouma, G. J. Tearney, and J. G. Fujimoto, "Optical frequency-domain reflectometry using rapid wavelength tuning of a Cr4+:forsterite laser," Opt. Lett. 22(22), 1704-1706 (1997). 16. S. R. Chinn, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography using a frequency-tunable optical source," Opt. Lett. 22(5), 340-342 (1997). 17. M. Wojtkowski, R. Leitgeb, A. Kowalczyk, T. Bajraszewski, and A. F. Fercher, "In vivo human retinal imaging by Fourier domain optical coherence tomography," J. Biomed. Opt. 7(3), 457-463 (2002). 18. L. Kranendonk, R. Bartula, and S. Sanders, "Modeless operation of a wavelength-agile laser by high-speed cavity length changes," Opt. Express 13(5), 1498-1507 (2005). 656-664 (2012). 36. C. Henry, "Theory of the linewidth of semiconductor lasers," IEEE J. Quantum Electron. 18(2), 259-264 (1982). 37. J. Geng, Q. Wang, J. Wang, S. Jiang, and K. Hsu, "All-fiber wavelength-swept laser near 2 μm," Opt. Lett. 3771-3773 (2011). 38. F. Nielsen, L. Thrane, J. Black, A. Bjarklev, and P. Ander...

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“…The endomicroscopic microscanners mainly divide into scanning mirror, a single optical fiber scanner [7,9,[14][15][16][17][18][19][20], or a lens scanner [13,[21][22][23][24]. First, the scanning MEMS mirrors are operated by using electrostatic [25][26][27][28][29][30][31], electromagnetic [22,32], or electrothermal [33][34][35][36][37][38][39] actuation.…”

Section: Actuation Mechanism Of Microscannersmentioning

confidence: 99%

Microscanners for optical endomicroscopic applications

Hwang

Seo

Jeong

2017

Micro and Nano Syst Lett

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MEMS laser scanning enables the miniaturization of endoscopic catheters for advanced endomicroscopy such as confocal microscopy, multiphoton microscopy, optical coherence tomography, and many other laser scanning microscopy. These advanced biomedical imaging modalities open a great potential for in vivo optical biopsy without surgical excision. They have huge capabilities for detecting on-demand early stage cancer with non-invasiveness. In this article, the scanning arrangement, trajectory, and actuation mechanism of endoscopic microscanners and their endomicroscopic applications will be overviewed.

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Rapid scanning catheterscope for expanded forward-view volumetric imaging with optical coherence tomography

Cited by 20 publications

References 21 publications

Combined optical coherence tomography and hyperspectral imaging using a double-clad fiber coupler

Combined optical coherence tomography and hyperspectral imaging using a double-clad fiber coupler

High-speed OCT light sources and systems [Invited]

Microscanners for optical endomicroscopic applications

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