Rapidly Progressing Aseptic Abscesses in a Patient with Ulcerative Colitis

Abstract

Aseptic abscesses (AAs) are extraintestinal manifestations of inflammatory bowel disease (IBD). IBDassociated AAs are rare in Japan. We treated a 45-year-old man with ulcerative colitis (UC)-associated AAs. During remission, multiple progressive abscesses were detected in the spleen; he underwent splenectomy because an infectious disease was suspected. Although his condition improved temporarily after splenectomy, a large liver abscess was noted, and a diagnosis of UC-associated AAs was made. Granulocytapheresis (GCAP) and infliximab (IFX) administration resolved the abscess. This is the first reported case of UC-associated AAs in a Japanese patient treated by splenectomy, GCAP, and IFX.

Hepatic Abscess in Inflammatory Bowel Disease: A Systematic Scoping Review of an Overlooked Entity

“…[ 48 ] Regarding the geographical distribution of articles, most of the studies were carried out in the United States ( n = 21), followed by the United Kingdom ( n = 4),[ 16 23 35 37 ] Spain ( n = 3),[ 30 36 44 ] and Japan ( n = 3). [ 38 51 60 ] Only one study was conducted in Saudi Arabia,[ 47 ] and just one article was published from the remaining Arabian Gulf Countries, from Kuwait. [ 22 ] The remaining studies were reported from Italy,[ 25 34 ] Israel,[ 27 28 ] France,[ 21 32 ] Korea,[ 55 ] Portugal,[ 53 ] Germany,[ 29 ] Turkey,[ 31 ] India,[ 39 ] China,[ 40 ] Switzerland,[ 45 ] Canada,[ 49 ] and The Netherlands.…”