Rare Case of Precursor B-Cell Acute Lymphoblastic Leukemia Presenting As a Solitary Paraspinal Mass Alone

Roy, Amitesh; Hawkes, Eliza A; Bardy, Peter; Woo, Tae Ho; Ting, Kimberley; Astill, David; Karapetis, Christos S.

doi:10.1200/jco.2012.47.2308

Cited by 4 publications

(1 citation statement)

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“…[7]. When there is more than 25 % blast in the bone marrow with or without mass lesion, the lesion is defined as lymphoid leukemia [8]. Primary vertebral location of non-Hodgkin lymphomas is rare and accounts for 1.7 % of all primary bone lymphoma [9].…”

Section: Discussionmentioning

confidence: 99%

A rare case of giant solitary spinal B cell lymphoblastic lymphoma

et al. 2016

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Background: Common B cell lymphoma locations are lymph nodes, skin, bone, mediastinum and it accounts for 2 % of NHL. Giant solitary spinal B-LBL has not yet been described. Case presentation: A 15-years old boy was admitted for a painful swelling of the thoracolumbar spine and paraplegia. MRI showed a voluminous mass of the thoracolumbar spine. Initial treatment consisted of surgical decompression and stabilization, followed by chemotherapy and radiotherapy. Histological examination showed a B-LBL. The quality of life improved significantly. Conclusion: To the best of our knowledge, this is the first case of giant solitary spinal B-LBL ever reported. Indication to choose a treatment method over another should weigh on individual priorities. Surgery should be considered as initial treatment option in this atypical lesion.

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Section: Discussionmentioning

confidence: 99%