2024
DOI: 10.21203/rs.3.rs-4347522/v1
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Rare host variants in ciliary expressed genes contribute to COVID-19 severity in Bulgarian patients

Kunka Kamenarova,
Darina Kachakova-Yordanova,
Magdalena Baymakova
et al.

Abstract: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), a pneumonia with extremely heterogeneous clinical presentation, ranging from asymptomatic to severely ill patients. Previous studies have reported links between the presence of host genetic variants and the outcome of the COVID-19 infection. In our study, we used whole exome sequencing in a cohort of 444 SARS-CoV-2 patients, admitted to hospital in the period October-2020-April-2022, to search for associati… Show more

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