Rare Primary Signet Ring Cell Carcinoma of the Bladder Cancer

Abstract

Primary signet ring cell carcinoma of the bladder is a rare tumor and it has a poor prognosis and is more mortal than the urothelial cell carnioma. However, most patients apply with painless macroscopic hematuria; rarely do they could apply with urinary tract infection or lower urinary tract symptoms. In this study; a 47-yearold male was referred to our clinic with dysuria, which was antibiotic therapy and symptomatic treatment. In ultrasonography, bladder wall thickening has been seen then patient underwent with cystoscopy. After atypical lesions were seen on the bladder mucosa, random punch biopsies were taken. A pathological examination revealed infiltrative urothelial carcinoma with a poorly differentiated signet ring cell component. As in this case report, patients with signet ring cell bladder cancer, which is rare and has an aggressive course, might only present with non-specific complaints such as dysuria. If atypical lesions are observed during the diagnostic cystoscopy procedure, the threshold should be kept low to decide on biopsy.