Rarely Observed Jumping Translocation in Spontaneous Abortion

Chromosomal instability in first trimester miscarriage: a common cause of pregnancy loss?

“…The first and second cases in the literature arose from meiotic alteration from a parental translocation (13,14). Four more cases in two manuscripts were presented where several cell lines were observed with donor chromosomes and different recipients; all of which were de novo events (25,26). An additional case of a slightly later pregnancy loss described a twin pregnancy with differing cytogenetic results involving the same donor chromosome (11).…”