Re: Comparative Assessment of Maximal Bladder Capacity, 0.9% Nacl Versus 0.2 M Kcl, for the Diagnosis of Interstitial Cystitis: A Prospective Controlled Study

Irwin, Paul; Samsudin, Azizan; Philip, Joe

doi:10.1097/01.ju.0000121861.63006.49

Cited by 6 publications

(1 citation statement)

References 4 publications

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“…The study, as designed, contains similar, albeit minor, shortfalls to those we identified previously in a study by Daha et al. [2], i.e. that the C max was not clearly defined by titration against functional bladder capacity (as determined by frequency‐volume diary) and that it is unclear whether the two fluid solutions were infused in addition to the patient’s postvoid residual volume or not.…”

mentioning

confidence: 99%

Influence of Intravesical Potassium on Pelvic Floor Activity in Women With Overactive Bladder Syndrome: Comparative Urodynamics Might Provide Better Detection of Dysfunctional Voiding

Irwin,

Philip

2008

BJU International

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confidence: 99%

Influence of Intravesical Potassium on Pelvic Floor Activity in Women With Overactive Bladder Syndrome: Comparative Urodynamics Might Provide Better Detection of Dysfunctional Voiding

Irwin,

Philip

2008

BJU International

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A double‐blind, randomized controlled trial of cystometry using saline versus 0.3 M potassium chloride infusion in women with overactive bladder syndrome

Philip

Willmott

Owen

et al. 2006

Neurourology and Urodynamics

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Aim: To evaluate the e¡ect of 0.3 M potassium chloride on cystometric parameters by comparing it with normal saline as a ¢lling solution in women with overactive bladder (OAB). Patients and Methods: Twenty-three women with signi¢cant OAB symptoms underwent consecutive cystometrograms (CMGs) using 0.9% normal saline (NS) and 0.3 M potassium chloride (KCl), the order of which was randomized for each patient. Individual CMGs were performed by separate investigators and both patients and investigators were blinded to the order in which each solution was given and to the results of the other CMG. Results: Regardless of the nature of the ¢lling solution, the order in which the CMGs were performed had little in£uence on either ¢rst desire to void (FDV, mean 83.5 ml vs. 117.8 ml for ¢rst and second CMGs respectively, P ¼ 0.10) or on maximum cystometric capacity (Cmax, mean 265.0 ml vs. 264.4 ml, P ¼ 0.98). KCl produced a signi¢cant (24%) reduction in mean Cmax compared to NS (mean 228.6 ml vs. 300.8 ml, P ¼ 0.001), irrespective of the order of infusion. Conclusion: This comparative study using 0.3 M KCl versus NS as ¢lling solutions suggests that intravesical potassium may not simply act on urothelial sensory nerve endings; it may also stimulate detrusor muscle contraction. These ¢ndings may in£uence the interpretation of the potassium sensitivity test in patients with OAB symptoms, particularly in those suspected of having interstitial cystitis.

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Urodynamics in BPS

Irwin

Riedl²

2012

Bladder Pain Syndrome

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Re: Comparative Assessment of Maximal Bladder Capacity, 0.9% Nacl Versus 0.2 M Kcl, for the Diagnosis of Interstitial Cystitis: A Prospective Controlled Study

Cited by 6 publications

References 4 publications

Influence of Intravesical Potassium on Pelvic Floor Activity in Women With Overactive Bladder Syndrome: Comparative Urodynamics Might Provide Better Detection of Dysfunctional Voiding

Influence of Intravesical Potassium on Pelvic Floor Activity in Women With Overactive Bladder Syndrome: Comparative Urodynamics Might Provide Better Detection of Dysfunctional Voiding

A double‐blind, randomized controlled trial of cystometry using saline versus 0.3 M potassium chloride infusion in women with overactive bladder syndrome

Urodynamics in BPS

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