Re: Dua et al.: Human corneal anatomy redefined: a novel pre-Descemet layer (Dua's layer) (Ophthalmology 2013;120:1778–85)

McKee, Hamish D.; Irion, Luciane; Carley, Fiona; Brahma, Arun; Jafarinasab, M R; Rahmati-Kamel, Mohsen; Kanavi, Mozhgan R.; Feizi, Sepehr

doi:10.1016/j.ophtha.2013.12.021

Cited by 32 publications

(16 citation statements)

References 4 publications

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“…(2013) proposed that the corneal stroma adjacent to Descemet's membrane was a distinct layer, which has different biomechanical properties to the rest of the stroma. The presence of a distinct new layer is controversial ( Jester et al., 2013 , Mckee et al., 2014 ) and it has been suggested that the plane above this so-called pre-Descemet's stromal layer is non-reproducibly determined by the variable distances of keratocytes to Descemet's membrane within and between corneas ( Schlotzer-Schrehardt et al., 2015 ). Nevertheless these developments have highlighted the need to explore in detail the structural and hence the biomechanical properties of the corneal stroma at all positions and depths, and this must include the elastic fibers as well as the collagen lamellae.…”

Section: Introductionmentioning

confidence: 99%

Three-dimensional arrangement of elastic fibers in the human corneal stroma

Lewis

White

Young

et al. 2016

Experimental Eye Research

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The cornea is the main refracting lens in the eye. As part of the outer tunic it has to be resilient, a property conferred by the organisation of the constituent collagen. It also has to be sufficiently elastic to regain its exact shape when deformed, in order not to distort the retinal image. The basis of this elasticity is not fully understood. The purpose of this study was to characterise in three dimensions the arrangement and distribution of elastic fibers in the human corneal stroma, using serial block face scanning electron microscopy. We have demonstrated that there exists a complex network of elastic fibers that appear to originate in the sclera or limbus. These appear as elastic sheets in the limbus and peripheral cornea immediately above the trabecular meshwork which itself appears to extend above Descemet's membrane in the peripheral stroma. From these sheets, elastic fibers extend into the cornea; moving centrally they bifurcate and trifurcate into narrower fibers and are concentrated in the posterior stroma immediately above Descemet's membrane. We contend that elastic sheets will play an important role in the biomechanical deformation and recovery of the peripheral cornea. The network may also have practical implications for understanding the structural basis behind a number of corneal surgeries.

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Section: Introductionmentioning

confidence: 99%

Three-dimensional arrangement of elastic fibers in the human corneal stroma

Lewis

White

Young

et al. 2016

Experimental Eye Research

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“…We feel that the recent report by Dua et al 2 and the ensuing controversy 3 have played a constructive role to highlight the surgical characteristics of the posterior stroma in deep lamellar dissections.…”

mentioning

confidence: 87%

Differentiating type 1 from type 2 big bubbles in deep anterior lamellar keratoplasty

Dua¹,

Katamish²,

Said³

et al. 2015

OPTH

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“…1): ). There remains contention [8,9] surrounding the potential existence of a postulated sixth corneal layer, Dua's layer [10], located between the stroma and posterior limiting lamina. The two posterior corneal layers are customarily presented as single values, although ranges are more accurate since their thickness changes throughout life.…”

Section: Gross Anatomymentioning

confidence: 99%

BCLA CLEAR - Anatomy and physiology of the anterior eye

Downie

Bandlitz

Bergmanson

et al. 2021

Contact Lens and Anterior Eye

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A key element of contact lens practice involves clinical evaluation of anterior eye health, including the cornea and limbus, conjunctiva and sclera, eyelids and eyelashes, lacrimal system and tear film. This report reviews the fundamental anatomy and physiology of these structures, including the vascular supply, venous drainage, lymphatic drainage, sensory innervation, physiology and function. This is the foundation for considering the potential interactions with, and effects of, contact lens wear on the anterior eye. This information is not consistently published as academic research and this report provides a synthesis from all available sources. With respect to terminology, the report aims to promote the consistent use of nomenclature in the field, and generally adopts anatomical terms recommended by the Federative Committee for Anatomical Terminology. Techniques for the examination of the ocular surface are also discussed.

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Re: Dua et al.: Human corneal anatomy redefined: a novel pre-Descemet layer (Dua's layer) (Ophthalmology 2013;120:1778–85)

Cited by 32 publications

References 4 publications

Three-dimensional arrangement of elastic fibers in the human corneal stroma

Three-dimensional arrangement of elastic fibers in the human corneal stroma

Differentiating type 1 from type 2 big bubbles in deep anterior lamellar keratoplasty

BCLA CLEAR - Anatomy and physiology of the anterior eye

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Re: Dua et al.: Human corneal anatomy redefined: a novel pre-Descemet layer (Dua's layer) (Ophthalmology 2013;120:1778–85)

Cited by 32 publications

References 4 publications

Three-dimensional arrangement of elastic fibers in the human corneal stroma

Three-dimensional arrangement of elastic fibers in the human corneal stroma

Differentiating type 1 from type 2 big bubbles in&nbsp;deep anterior lamellar keratoplasty

BCLA CLEAR - Anatomy and physiology of the anterior eye

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Differentiating type 1 from type 2 big bubbles in deep anterior lamellar keratoplasty