Re: Mirena Coil is a suitable treatment of early stage endometrial cancer in obese women: FOR or AGAINST?

Authors' reply re: Mirena Coil is a suitable treatment of early‐stage endometrial cancer in obese women: FOR or AGAINST?

“…We completely agree with Mr Iavazzo and colleagues, 1 who state that hysterectomy is standard management for earlystage endometrial cancer. In most cases, it is a straightforward decision, an uncomplicated procedure, a quick return to health that offers long-term cure for the patient.…”

“…We read with interest the recent article by Vousden et al 1 on pregnancy-related death in low-income countries. It was reported that hypertensive disorders during pregnancy (HDDP) are a leading cause of maternal and perinatal mortality and morbidity with direct estimated maternal deaths of about 41 000 per year (14% of all maternal deaths), of whom 94% occur in low-income countries.…”

“…2,3 The scenario is worse in low-income countries, 4 where HDDP represent the highest share of poor maternal and perinatal outcomes along with haemorrhage. 1,2 The main strength of the CRADLE study is the direct collection of data that do not suffer from inadvertent errors (misclassification, misinterpretation of coding rules, omissions, incorrect entries) as found in studies that rely on cause-ofdeath coding or aggregated cause-ofdeath fractions. Furthermore, this inaccuracy is even more pronounced for data obtained in low-income countries.…”

“…Recently, we carried out a retrospective analysis of 4 years (2016-2019) based on maternity data obtained from the internal survey of four district hospitals (three in the city and one in a rural area) of Sierra Leone to picture the real situation in one of the countries with the highest rates of maternal and perinatal mortality shown by the CRADLE study. 1 In the past years, Doctors with Africa CUAMM (nongovernmental organizations focused on healthcare, https://doctorswithafrica.org/ en/) started a comprehensive project in Sierra Leone, Africa, to promote maternal, neonatal, child and adolescent health by giving direct local support to hospitals. They set up an active systematic weekly based revision of clinical notes for administrative and clinical governance with monthly reports.…”