“…Most cases of intracranial haemorrhage in the newborn originate in the germinal matrix, are diagnosed within the first week of life, and occur in the premature baby (Papile et al, 1978;Skinner et al, 1982;Lebed et al, 1982;Shaver et al, 1992). The causative mechanism is unclear; it is proposed that the germinal matrix is friable and fragile until about 32-34 weeks' gestation, and is highly susceptible to hypoxaemia and anoxia, to acidosis disturbances, and to fluxes in blood pressure.…”