Real-Time Contrast-Enhanced–Guided Biopsy Compared with Conventional Ultrasound–Guided Biopsy in the Diagnosis of Hepatic Tumors on a Background of Advanced Chronic Liver Disease: A Prospective, Randomized, Clinical Trial

Spârchez, Zeno; Mocan, Tudor; Hagiu, Claudia; Kacsó, Gabriel; Zaharie, Toader; Rusu, Ioana; Hajjar, Nadim Al; Leucuţa, Daniel; Spârchez, Mihaela

doi:10.1016/j.ultrasmedbio.2019.07.678

Cited by 19 publications

(22 citation statements)

References 26 publications

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“…Contrast-enhanced ultrasound may be of use in those with advanced chronic liver disease. 1 A blind liver biopsy is where the biopsy is done without imaging guidance. The guidelines state that a blind liver biopsy should not be performed without recent liver imaging (within the preceding 3 months) and this imaging should be reviewed before undertaking a biopsy.…”

Section: Percutaneous Liver Biopsymentioning

confidence: 99%

Guidelines on the use of liver biopsy in clinical practice from the British Society of Gastroenterology, the Royal College of Radiologists and the Royal College of Pathology

Neuberger

Patel

Caldwell

et al. 2020

Gut

255

201

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Liver biopsy is required when clinically important information about the diagnosis, prognosis or management of a patient cannot be obtained by safer means, or for research purposes. There are several approaches to liver biopsy but predominantly percutaneous or transvenous approaches are used. A wide choice of needles is available and the approach and type of needle used will depend on the clinical state of the patient and local expertise but, for non-lesional biopsies, a 16-gauge needle is recommended. Many patients with liver disease will have abnormal laboratory coagulation tests or receive anticoagulation or antiplatelet medication. A greater understanding of the changes in haemostasis in liver disease allows for a more rational, evidence-based approach to peri-biopsy management. Overall, liver biopsy is safe but there is a small morbidity and a very small mortality so patients must be fully counselled. The specimen must be of sufficient size for histopathological interpretation. Communication with the histopathologist, with access to relevant clinical information and the results of other investigations, is essential for the generation of a clinically useful report.

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Section: Percutaneous Liver Biopsymentioning

confidence: 99%

Guidelines on the use of liver biopsy in clinical practice from the British Society of Gastroenterology, the Royal College of Radiologists and the Royal College of Pathology

Neuberger

Patel

Caldwell

et al. 2020

Gut

255

201

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“…1,2 In cases of both biopsy and ablative maneuvers, CEUS is of pivotal importance in the planning phase, since it provides information on the real size, boundaries, and internal vascularization of the target lesion. 1,2 Similarly, some selected cases of focal liver lesions (poorly visualized or invisible at the B-mode US examination or partially necrotic with limited viable areas) can be approached by driving bioptic 3,4 or therapeutic needles to the targets under CEUS guidance. 5 Furthermore, immediately after thermal ablation of neoplastic liver nodules, CEUS has a well-established role in detecting residual viable areas to allow prompt retreatment and reduction of both the number of ablative sessions and the cost per patient for achieving complete treatment.…”

mentioning

confidence: 99%

“…In cases of both biopsy and ablative maneuvers, CEUS is of pivotal importance in the planning phase, since it provides information on the real size, boundaries, and internal vascularization of the target lesion 1,2 . Similarly, some selected cases of focal liver lesions (poorly visualized or invisible at the B‐mode US examination or partially necrotic with limited viable areas) can be approached by driving bioptic 3,4 or therapeutic needles to the targets under CEUS guidance 5 …”

mentioning

confidence: 99%

Role of Contrast‐Enhanced Ultrasound in the Detection of Complications After Ultrasound‐Guided Liver Interventional Procedures

Francica

Meloni

Riccardi³

et al. 2020

J of Ultrasound Medicine

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The role of contrast-enhanced ultrasound (CEUS) in interventional ultrasoundguided procedures in the liver has been increasingly recognized. However, little is known about the capability of CEUS for diagnosing complications after liver biopsy and ablation with special regard to postprocedural hemorrhage. The aim of this Pictorial Essay is to present the CEUS features of a wide spectrum of vascular complications (with or without bleeding) and injuries of the surrounding abdominal and chest wall occurring after liver interventional procedures.

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“…abscesses in pneumonia) (24)(25)(26). Not least, CEUS expands relevance for patchy tumoral organ involvement, such as lymph nodes or prostatic adenocarcinoma (13).…”

Section: A C C E P T E D a R T I C L Ementioning

confidence: 99%

Contrast enhancement for ultrasound-guided interventions: when to use it and what to expect?

Spârchez¹,

Mocan²,

Crăciun³

et al. 2022

Ultrasonography

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The use of contrast enhancement in ultrasonography (CEUS) has become synonymous with high standard ultrasonography (US) in the recent past. From expanding the reach of US diagnostics to improving the precision of various invasive procedures, CEUS is rapidly becoming a standard in numerous niches. However, proficiency in CEUS comes with a cost, both from a learning curve and material standpoint, and as every growing field, lacks firm evidence and standardization.Therefore, in the current paper, we aim to provide an evidence-based review of available methods and to discuss the perks and pitfalls of CEUS in interventional procedures, trying to provide strong evidence whenever available, or at least an educated expert opinion if data is lacking.

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Real-Time Contrast-Enhanced–Guided Biopsy Compared with Conventional Ultrasound–Guided Biopsy in the Diagnosis of Hepatic Tumors on a Background of Advanced Chronic Liver Disease: A Prospective, Randomized, Clinical Trial

Cited by 19 publications

References 26 publications

Guidelines on the use of liver biopsy in clinical practice from the British Society of Gastroenterology, the Royal College of Radiologists and the Royal College of Pathology

Guidelines on the use of liver biopsy in clinical practice from the British Society of Gastroenterology, the Royal College of Radiologists and the Royal College of Pathology

Role of Contrast‐Enhanced Ultrasound in the Detection of Complications After Ultrasound‐Guided Liver Interventional Procedures

Contrast enhancement for ultrasound-guided interventions: when to use it and what to expect?

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