Real-Time Elastography (Rte) in Patients With Peyronie's Disease: First Results of a New Imaging Technique for the Detection and Mesurement of Plaques

Lahme, Sven; Zimmermanns, V.; Liske, P.; Ober, Philipp

doi:10.1016/s0022-5347(09)60797-7

Cited by 3 publications

(7 citation statements)

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“…In our review, we found four articles where this technique was used in the more in-depth diagnosis of PD. All of the authors that used this technique emphasized its clinical utility in identifying non-palpable Peyronie’s plaques and in evaluating plaque rigidity [ 38 , 39 , 40 , 47 ]. While the use of SE in combination with the analysis of semi-quantitative parameters may not be as quick as simple visual observation, it appears to offer more objective data and is better suited for tracking the progression of PD.…”

Section: Discussionmentioning

confidence: 99%

“…The main limitation of this study is that our review is simply a narrative review and not a systematic one (e.g., following PRISMA guidelines). Another limitation of our article is that both the article by Lahme et al and the case report article by Dhawan et al mentioned above do not explicitly mention the brands or models of the ultrasound equipment used in their studies [ 38 , 47 ]. This omission could be considered a limitation because knowing the exact device allows readers to better understand potential variations in image quality, performance, and reliability between different machines.…”

Section: Discussionmentioning

confidence: 99%

“…In this pioneering study, which was the first of its kind, real-time elastography (RTE) was used in patients with PD [ 38 ]. The published article refers to a presentation given at the American Urological Association’s 2009 Annual Meeting (Chicago, IL, USA).…”

Section: Relevant Sectionsmentioning

confidence: 99%

“…Elastography is a noninvasive method used in tandem with an ultrasound probe to measure the mechanical properties of tissue that may be more rigid due to alterations caused by a pathological process. The first diagnostic approaches with elastography began at the end of the last century and were followed by numerous scientific studies [ 38 ]. Elastography is mainly used for soft tissue pathologies, such as tissues of the liver, breast, prostate, thyroid, pancreas, nerves, tendons, and muscles.…”

Section: Introductionmentioning

confidence: 99%

“…Elastography is mainly used for soft tissue pathologies, such as tissues of the liver, breast, prostate, thyroid, pancreas, nerves, tendons, and muscles. More recently, elastography has also been proposed for the study of PD [ 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 ]. Commercial elastography equipment was initially introduced in 2003 and has seen significant advancements over the past two decades.…”

Section: Introductionmentioning

confidence: 99%

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Ultrasound Elastography as a Diagnostic Tool for Peyronie’s Disease: A State-of-the-Art Review

Paulis,

De Giorgio,

Paulis

2024

Diagnostics

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Elastography is a noninvasive method that utilizes ultrasound imaging to assess the elasticity and stiffness of soft tissue. Peyronie’s disease (PD) is a chronic inflammatory condition that affects the male penis, causing the formation of fibrous plaques. This alters the penis’s elasticity and can lead to changes in its shape. Ultrasound elastography (UE) is an important advancement in the diagnosis of PD. It not only identifies plaques, but it also measures their rigidity, providing crucial information to monitor changes during and after treatment. We conducted a narrative review of the scientific literature to identify articles that discuss the use of elastography in the diagnostic study of PD. The purpose of this study was to describe the “state of the art” in the diagnostic use of ultrasound in combination with elastography to highlight any benefits in the diagnosis of PD. We found 12 relevant articles after searching PubMed, Embase, and Google Scholar using the keywords “ultrasound elastography” and “Peyronie’s disease”, including eight clinical studies, two case reports, and two review articles. The results of our review indicate that UE is a useful technique for identifying Peyronie-related plaques, particularly when they are not detectable using a standard ultrasound or physical examination. It is also helpful in monitoring improvements during and after conservative treatments. More research is required to confirm the effectiveness of ultrasound elastography in diagnosing Peyronie’s disease and to determine whether it is better than traditional ultrasound.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Relevant Sectionsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Ultrasound Elastography as a Diagnostic Tool for Peyronie’s Disease: A State-of-the-Art Review

Paulis,

De Giorgio,

Paulis

2024

Diagnostics

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Clinical Presentation of Peyronie’s Disease: A Retrospective Study of 564 Cases

Paulis,

De Giorgio,

Paulis

2024

Diagnostics

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Peyronie’s disease (PD) affects the penile albuginea, resulting in penile deformity, pain, erectile dysfunction (ED), and an anxious–depressive state. PD diagnosis involves a thorough medical history, penile palpation, documentation of the penile deformation, a dynamic penile echo color Doppler ultrasound (PCDU), and the completion of questionnaires for the evaluation of pain, ED, and psychometric tests. The aim of this study was to evaluate the symptoms of PD and their prevalence in PD patients in the active phase who had access to our andrology clinic. Inclusion criteria: availability of data on patients diagnosed with PD, including detailed medical history, blood tests, penile palpation, photographic documentation of penile deformity, and penile PCDU. Exclusion criteria: PD patients in the stable phase or those without the specified tests and data mentioned above. Our study found a higher prevalence of PD in younger patients (24.2%), a higher coexistence of PD with chronic prostatitis (35.6%), a higher percentage of cases of association between penile deformity and penile curvature (84.4%), a higher prevalence of “significant anxiety” (88.4%), a higher presence of plaque calcification (35.6%), and the detection of a longer duration of the first phase of PD (>18 months). The most frequently observed type of penile curvature was dorsal, followed by left lateral, right lateral, and, less commonly, ventral. We observed a significant statistical correlation between patient age and IIEF score, indicating that patients over the age of 40 years are at a higher risk of experiencing ED. We found a strong statistical relationship between VAS score and age. As age increases, the VAS score decreases, suggesting that younger patients reported more penile pain compared to those who were older than 40 years. Furthermore, we found that penile pain has a significant impact on the psychological state of PD patients. We also found that 38.8% of PD patients suffered from severe anxiety. In relation to this, psychotherapy should be integrated into PD treatment to improve the quality of life and treatment adherence.

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Combining ultrasound and elastography for the detection of a non-palpable, non-sonographically visualized Peyronie's plaques. Our experience

Paulis,

De Giorgio,

Paulis

2024

Arch Ital Urol Androl

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Background: B-mode ultrasound (US) medical imaging is very effective in localizing and describing Peyronie's disease (PD). Moreover, elastography is a new technique used to evaluate tissue elasticity to detect penile Peyronie's plaques that are not visible using standard B-mode US. Objective: The main objective of this study was to evaluate the diagnostic efficacy of real-time elastography (RTE) in PD patients and to determine whether its combined use with standard US improved diagnostic accuracy. RTE is also known as strain elastography (SE). Additionally, this study aimed to assess whether RTE was useful for monitoring PD patients undergoing conservative treatment.Methods: A group of 37 PD patients in the active phase was selected based on US examination showing isoechoic or hypo-isoechoic plaques, with or without associated hyperechoic or calcified plaque areas. All patients underwent traditional US combined with RTE before starting conservative treatment with antioxidants, during treatment and after treatment. After each examination with RTE, a specific “Strain Ratio”(SR) was used to identify the specific elasticity of the tissue. Results: Using B-mode US with RTE, we detected all 13 non-palpable penile plaques present in the 37 PD patients (100% of cases). Using only B-mode US, we detected only 8 of the 13 non-palpable plaques (61.5% of cases). The DI of the plaque decreased during and after treatment in all cases, indicating that RTE is effective for monitoring conservative PD treatment. A statistically significant correlation was found between the DI and plaque volume in all patients (p=0.002). Conclusion: Our study has shown that the combination of US and RTE methods allowed for a more accurate diagnosis in PD patients.

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Real-Time Elastography (Rte) in Patients With Peyronie's Disease: First Results of a New Imaging Technique for the Detection and Mesurement of Plaques

Cited by 3 publications

References 0 publications

Ultrasound Elastography as a Diagnostic Tool for Peyronie’s Disease: A State-of-the-Art Review

Ultrasound Elastography as a Diagnostic Tool for Peyronie’s Disease: A State-of-the-Art Review

Clinical Presentation of Peyronie’s Disease: A Retrospective Study of 564 Cases

Combining ultrasound and elastography for the detection of a non-palpable, non-sonographically visualized Peyronie's plaques. Our experience

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