Background: Conventional echocardiography is not sensitive enough to assess the mild acute myocardial infarction (AMI), especially the non ST elevation AMI (NSTEAMI) that the myocardial motion is often normal or mildly reduced. This research attempt to find some new technology to better assess the left ventricular (LV) volume and myocardial function after percutaneous coronary intervention (PCI) in the elderly patients with NSTEAMI and ST elevation AMI (STEAMI). Methods: Patients with NSTEAMI (n=40) and STEAMI (n=40) underwent imaging investigations 1 week and 3 months after PCI. A group of 40 healthy volunteers was used as a control group. The LV end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), and ejection fraction (EF) were measured using real-time three-dimensional echocardiography (RT-3DE). The longitudinal peak systolic strain (LPSS), radial peak systolic strain (RPSS), circumferential peak systolic strain (CPSS) and rotational peak degree (Rot) in the myocardium supplied by infarct-related artery (Myo-IRA) segments (LPSS-Api, LPSS-Mid, LPSS-Bas, RPSS-Api, RPSS-Mid, RPSS-Bas, CPSS-Api, CPSS-Mid, CPSS-Bas, Rot-Bas, Rot-Api) were obtained using two-dimensional speckle tracking imaging (2D-STI). The peak torsion angle (Twist) were calculated. Results: Compared with control group, in 1 week after PCI, the ESV and EDV in NSTEAMI and STEAMI patients were significantly increased (P<0.001), the LPSS, RPSS, CPSS in the Myo-IRA segments and the EF, SV, Rot-bas, Rot-Api and Twist in the NSTEAMI and STEAMI patients were significantly lower (P<0.001), and more so in the STEAMI patients. Compared with 1 week after PCI, in 3 months after PCI, the ESV, EDV, SV, EF, RPSS, CPSS, Rot-Bas and Twist in NSTEAMI and STEAMI patients were recovered partially (P<0.01), the LPSS and Rot-Api only in the NSTEAMI patients was improved significantly (P<0.01). Conclusions: The LV volume functions, longitudinal, radial, circumferential, and twist movement in the elderly AMI patients with different degree of transmural damage 1 week and 3 months after PCI can be objectively and sensitively revealed by using RT-3DE and 2D-STI respectively. The LV myocardial multi-dimensional deformation functions are severely damaged in both NSTEAMI and STEAMI patients, but the NSTEAMI patients have a better prognosis after treatment over a long time.