2020
DOI: 10.1101/2020.10.27.20217356
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Real-world, Prospective, and Multicenter Validation of a microRNA-based Thyroid Molecular Classifier

Abstract: Background The diagnosis of cancer in thyroid nodules with indeterminate cytology (Bethesda III/IV) is challenging as fine-needle aspiration (FNA), the gold standard method, has limitations, and these cases usually require diagnostic surgery. As approximately 77% of these nodules are not malignant, a diagnostic test accurately identifying benign thyroid nodules can reduce surgery rates. We have previously reported the development and validation of a microRNA-based thyroid molecular classifier for precision end… Show more

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