Recent advance in fabricating monolithic 3D porous graphene and their applications in biosensing and biofuel cells

Qiu, Hua‐Jun; Guan, Yongxin; Luo, Pan; Wang, Yu

doi:10.1016/j.bios.2015.12.029

Cited by 108 publications

(31 citation statements)

References 76 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the case of chips, either many small electrodes, which can be controlled separately, are collocated, or the classical 3-electrode configuration is implemented. 96,181,292,[332][333][334][335][336][337][338][339][340][341][342][343][344][345][346] Detection limits for H 2 O 2 range from 10 nM up to 3 mM.…”

Section: G87mentioning

confidence: 99%

Review—Quantification of Hydrogen Peroxide by Electrochemical Methods and Electron Spin Resonance Spectroscopy

Gulaboski

Mirčeski

Kappl

et al. 2019

J. Electrochem. Soc.

View full text Add to dashboard Cite

Reactive oxygen species (ROS) exhibit different spatial and temporal distributions as well as concentrations in-and outside the cell, thereby functioning as signaling or pathogen-destroying molecules. Especially the ROS H 2 O 2 is important for the patho/physiological status of an organism. Electrochemistry (EM) and electron spin resonance (ESR)-based techniques allow quantification of H 2 O 2 in artificial and living systems, coping a concentration range from low nM up to mM. Working electrodes for EM are optimized by diverse modifications and, additionally, redox mediators are used. Ultramicroelectrodes allow scanning of single cells to spatially resolve and quantify extracellular H 2 O 2 in real-time. With ESR spectroscopy, • O 2¯, but not H 2 O 2 , can be directly determined by spin probes in-and outside of cells in suspensions. Monitoring H 2 O 2 requires formation of intermediate radicals, detectable with spin probes. Low μM [H 2 O 2 ] can thus be assessed specifically. Using suitable spin traps, in-vivo ESR and immuno-spin trapping can visualize different radicals at their respective production sites in small animals, organs and tissues. Here, the redox reaction cascades may interfere with cell metabolism. Optimization of all methods established for H 2 O 2 determination would be favorable to finally combine them for mutual validation. Thus, a deeper insight into cellular ROS metabolism can be obtained.

show abstract

Section: G87mentioning

confidence: 99%

Review—Quantification of Hydrogen Peroxide by Electrochemical Methods and Electron Spin Resonance Spectroscopy

Gulaboski

Mirčeski

Kappl

et al. 2019

J. Electrochem. Soc.

View full text Add to dashboard Cite

show abstract

“…These properties make 3D graphene a perfect candidate as a high-performance electrode material for biosensing. 22 In our previous studies, we have shown that GO hydrogel electrode is highly sensitive for DNA detection due to its bionic structure and tunable conductivity. 23 In this study, a novel GO/GNPs composite hydrogel biosensor for AβO detection was constructed.…”

mentioning

confidence: 99%

A hydrogel biosensor for high selective and sensitive detection of amyloid-beta oligomers

Sun

Zhong

Gui

et al. 2018

IJN

View full text Add to dashboard Cite

Background Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive cognitive and memory impairment. It is the most common neurological disease that causes dementia. Soluble amyloid-beta oligomers (AβO) in blood or cerebrospinal fluid (CSF) are the pathogenic biomarker correlated with AD. Methods A simple electrochemical biosensor using graphene oxide/gold nanoparticles (GNPs) hydrogel electrode was developed in this study. Thiolated cellular prion protein (PrP C ) peptide probe was immobilized on GNPs of the hydrogel electrode to construct an AβO biosensor. Electrochemical impedance spectroscopy was utilized for AβO analysis. Results The specific binding between AβO and PrP C probes on the hydrogel electrode resulted in an increase in the electron-transfer resistance. The biosensor showed high specificity and sensitivity for AβO detection. It could selectively differentiate AβO from amyloid-beta (Aβ) monomers or fibrils. Meanwhile, it was highly sensitive to detect as low as 0.1 pM AβO in artificial CSF or blood plasma. The linear range for AβO detection is from 0.1 pM to 10 nM. Conclusion This biosensor could be used as a cost-effective tool for early diagnosis of AD due to its high electrochemical performance and bionic structure.

show abstract

“…When coming to the discussion of bioapplication, deoxyribonucleic acid (DNA) translocation through nanoholes has been achieved [10]. Biosensing and biofuel applications have been developed [11]. Graphene nanohole based eletrocatalysts have been developed [12].…”

Section: Introductionmentioning

confidence: 99%

Review on Fabrication of Graphene Nanoholes

Silpa

Sivamangai

2019

e-J. Surf. Sci. Nanotechnol.

View full text Add to dashboard Cite

Graphene, an ultra-thin derivative of carbon, has hindered a lot of applications because of its unique characteristics. It was found that superb improvements on properties can be made on further by creating nanopores or nanoholes on the surface of the graphene film. Such holed graphene can be used in energy storage, fuel cells, biosensors, biochemical applications, plasmonic tweezers, etc. This is because pores can contribute toward more surface area and eventually toward transportation and storage for electron/ion, gas, and liquid. This paper is a review of graphene nanohole fabrication methods.

show abstract

Recent advance in fabricating monolithic 3D porous graphene and their applications in biosensing and biofuel cells

Cited by 108 publications

References 76 publications

Review—Quantification of Hydrogen Peroxide by Electrochemical Methods and Electron Spin Resonance Spectroscopy

Review—Quantification of Hydrogen Peroxide by Electrochemical Methods and Electron Spin Resonance Spectroscopy

A hydrogel biosensor for high selective and sensitive detection of amyloid-beta oligomers

Review on Fabrication of Graphene Nanoholes

Contact Info

Product

Resources

About