Recent Advance in the Synthesis of Natural Products of Schisandra Triterpenoid

Abstract

Schisandraceae is widely spread within our country. As a kind of traditional Chinese herb, it is known for its anti-hepatitis bioactivity. The diversified and unique structures in this family have drawn the attention of many synthetic chemists. The recent efforts towards the total synthesis of schisandra triterpenoid are summarized.

Synthesis of the ABC ring system of kadlongilactones

“…Recently, the total synthesis of Schisandraceae triterpenoids has attracted great interest from synthetic organic chemists. 3,4 Several elegant syntheses have been elaborated by the groups of Yang, 5 Li, 6 Anderson, 7 Tang, 8 Ding, 9 and Gui. 10 However, the pharmaceutical value of Schisandraceae triterpenoids has not been fully elucidated, mainly because of the lack of a potential Schisandraceae triterpenoid lead for further medicinal study.…”