Recent advancements in coordination compounds and their potential clinical application in the management of diseases: An up-to-date review

Search for new biologically active compounds: in vitro studies of antitumor and antimicrobial activity of dirhodium(ii,ii) paddlewheel complexes

“…[7][8][9][10] Despite this fact, platinum-based drugs are still used as the first choice in more than 60% of treatment cases. 11, 12 An ideal anticancer drug must be able to destroy tumor cells while leaving the adjacent healthy tissue unharmed. Against this background, many research groups around the world have focused their research on the discovery of potential antitumor agents.…”

Improving the In Vivo Stability of [52Mn]Mn(II) Complexes with 18-Membered Macrocyclic Chelators for PET Imaging

“…Harnessing the properties of the metallic elements in vivo for medicinal applications most often requires the input of the field of coordination chemistry. − The formation of coordination compounds allows safe delivery of the metallic element into the body, avoiding negative side effects related to the release of metal. Coordination compounds are used for various biomedical applications, including both therapy and imaging. , Medical imaging requires the use of metal complexes for different techniques, such as the contrast agents used in magnetic resonance imaging (MRI), which are most often coordination compounds based on gadolinium­(III).…”

“…Harnessing the properties of the metallic elements in vivo for medicinal applications most often requires the input of the field of coordination chemistry. 1 − 3 The formation of coordination compounds allows safe delivery of the metallic element into the body, avoiding negative side effects related to the release of metal. Coordination compounds are used for various biomedical applications, including both therapy and imaging.…”

Complexes of Ruthenium(II) as Promising Dual-Active Agents against Cancer and Viral Infections

“…For many years, numerous researchers have actively worked in the field of inorganic drugs developing several metal complexes with diverse biological activities [1], such as anticancer [2][3][4][5][6][7][8] antibacterial [9], antioxidant [10], and antiviral [11][12][13]. During the COVID-19 pandemic [14], numerous studies have addressed using metal complexes in the hope of finding new strategies to cure the disease [15][16][17].…”