Recent advances in amino acid analysis by capillary electrophoresis

Abstract

Amino acids are studied extensively using capillary electrophoresis. In a previous article, we reviewed applications reported in the period 1999-early 2001 (Prata, C., Bonnafous, P., Fraysse, N., Treilhou, M., Poinsot, V., Couderc, F., Electrophoresis 2001, 22, 4129-4138). In this article we follow on with this review for the period end of 2001-beginning of 2003. We will report the developments of detection methods, separations of enantiomers, the new medical applications, and amino acids in food and plants. This review shows that CE is more and more important for the amino acid analysis.

Recent advances in the application of capillary electromigration methods for food analysis

“…Several reviews have been published on the application of CE methods in food analysis in the last three years, which is a good demonstration of the possibilities of this technique in this particular field. Table 1 summarizes the different reviews published on this topic [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19], including the aforementioned review by Frazier and Papadopoulou [1].…”

Development of a temperature gradient focusing method for in situ extraterrestrial biomarker analysis

“…For chiral amino acids separation, CDs are the most commonly used chiral selective additives [38][39][40][41]. In our case, because of the low temperature range used (3-307C), hydroxypropyl-b-CD (HPbCD) was selected due to its better solubility at low temperature.…”

Bioanalytical profile of the l-arginine/nitric oxide pathway and its evaluation by capillary electrophoresis

“…Microdialysis and push-pull sampling in combination with HPCE has been proposed as a versatile technique to determine the concentration of neurotransmitters and other biologically active substances under physiological conditions and upon drug administration in animal models [388][389][390][391][392]. Sakamoto et al [393] used in vivo brain dialysis and CZE analysis of NO 2 − and NO 3 − to study the effects of mild hypothermia on trauma-induced synthesis of NO in the rat parietal cortex after traumatic brain injury.…”