Recent Advances in Chiral Resolution Through Membrane‐Based Approaches

Afonso, Carlos A. M.; Crespo, João G.

doi:10.1002/chin.200502242

Cited by 8 publications

(11 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…139 The ionic liquid allowed enantioselective transport of the ibuprofen enantiomer across the membrane reactor. 132 Ionic liquids increased the selectivity and activity of the enzymatic membrane process. 140 The cross-flow filtration technique is commonly used to adsorb enzymes onto the HFM surfaces.…”

Section: Further Needsmentioning

confidence: 99%

“…Commonly one isomer is transported to the aqueous phase as product and the unreacted enantiomer remains in the organic phase. 78,132,133 Multiphase operation of the TSP-EMR has considerable advantages for enzymatic optical resolution when the substrates are poorly water-soluble and the products dissolve in water. 78 …”

Section: Application Of Tsp-emr: Immobilized Enzymes Resolution Of Ramentioning

confidence: 99%

See 1 more Smart Citation

Enzymatic membrane reactors: the determining factors in two separate phase operations

Agustian¹,

Kamaruddin²,

Bhatia³

2011

J of Chemical Tech & Biotech

View full text Add to dashboard Cite

A two separate phase-enzymatic membrane reactor is an attractive process since it has a large interfacial area and exchange surfaces, simultaneous reaction and separation and other benefits. Many factors influence its successful operation, and these include characteristics of the enzyme, membrane, circulating fluids and reactor operations. Although the operating conditions are the main factor, other factors must be considered before, during or after its application. At the initial stage of reactor development, the solubility of substrates and products, type of operation, membrane material and size, enzyme preparation and loading procedure, and cleanliness of the recirculated fluids should be specified. The immobilization site, reactor arrangement, dissolved or no-solvent operation, classic or emulsion operation and immobilized or suspended enzyme(s) are determined later. Some factors still need further studies. Utilization of the technology is described for use from multigram-to plant-scale capacity to process racemic and achiral compounds. The racemates were resolved primarily by kinetic resolution, but dynamic kinetic resolution has been exploited. The technology focused on hydrolytic reactions, but esterification processes were also exploited.

show abstract

Section: Further Needsmentioning

confidence: 99%

Section: Application Of Tsp-emr: Immobilized Enzymes Resolution Of Ramentioning

confidence: 99%

Enzymatic membrane reactors: the determining factors in two separate phase operations

Agustian¹,

Kamaruddin²,

Bhatia³

2011

J of Chemical Tech & Biotech

View full text Add to dashboard Cite

show abstract

“…The Freundlich and langmuir adsorption isotherm models indicated a spontaneous and endothermic adsorption of the organic dyes via internal transport or a diffusion mechanism facilitated by the keratinous structure of feather 74,80 . Membrane-based chiral separation is regarded as an ecologically and economically promising method to obtain enantiomerically pure and precious compounds, and has potential applications in chemical industries involving pharmaceuticals, agrochemicals, fragrances and food additives 61,81,82 . In one study, chicken feather degraded by Meiothermus ruber H328 thermophilic bacteria was converted into chiral separation membranes using 1-octane thiol as a reducing agent.…”

Section: Removal Of Organic Compoundsmentioning

confidence: 99%

Keratinous Materials as Novel Absorbent Systems for Toxic Pollutants

Ghosh¹,

Collie²

2014

DSJ

View full text Add to dashboard Cite

“…In addition to this, it is a promising and potentially convenient method to obtain enaniomerically pure compounds [8][9][10][11], since it can be operated continuously under mild conditions.…”

Section: Introductionmentioning

confidence: 99%

Electrospun nanofiber membranes from polysulfones with chiral selector aimed for optical resolution

Mizushima

Yoshikawa

et al. 2012

European Polymer Journal

View full text Add to dashboard Cite

/npsi/ctrl?action=rtdoc&an=20637155&lang=en http://nparc.cisti-icist.nrc-cnrc.gc.ca/npsi/ctrl?action=rtdoc&an=20637155&lang=fr READ THESE TERMS AND CONDITIONS CAREFULLY BEFORE USING THIS WEBSITE.http://nparc.cisti-icist.nrc-cnrc.gc.ca/npsi/jsp/nparc_cp.jsp?lang=en Vous avez des questions? Nous pouvons vous aider. Pour communiquer directement avec un auteur, consultez la première page de la revue dans laquelle son article a été publié afin de trouver ses coordonnées. Si vous n'arrivez pas à les repérer, communiquez avec nous à PublicationsArchive-ArchivesPublications@nrc-cnrc.gc.ca. Questions?Contact the NRC Publications Archive team at PublicationsArchive-ArchivesPublications@nrc-cnrc.gc.ca. If you wish to email the authors directly, please see the first page of the publication for their contact information. NRC Publications Archive Archives des publications du CNRCThis publication could be one of several versions: author's original, accepted manuscript or the publisher's version. / La version de cette publication peut être l'une des suivantes : la version prépublication de l'auteur, la version acceptée du manuscrit ou la version de l'éditeur. For the publisher's version, please access the DOI link below./ Pour consulter la version de l'éditeur, utilisez le lien DOI ci-dessous.http://doi.org/10.1016/j.eurpolymj.2012.07.003European Polymer Journal, 48, 10, pp. 1717Journal, 48, 10, pp. -1725Journal, 48, 10, pp. , 2012 ABSTRACTPolysulfones with three types of alanyl residues, such as N-!-acetylalanine (Ac-Ala-OH), N-!-benzoylalanine (Bzo-Ala-OH), and N-!-benzyloxycarbonylalanine (Z-Ala-OH), as chiral selectors were prepared by polymer reaction. The resulting modified polysulfones showed chiroptical properties, indicating that the chiral selector residues were successfully introduced into the polysulfone. Nanofiber membranes prepared from the polymeric materials showed adsorption selectivity toward mixtures of racemic Glu, which were adopted as model racemates. Flux values for the nanofiber membranes were enhanced two to three orders of magnitude in comparison with the corresponding typical membranes, but without reduction in permselectivity. In the present study, it is shown that nanofiber is a suitable membrane form not only for molecularly imprinted membranes, but it exhibits enhanced throughput in comparison with typical dense membranes without concurrent reduction in permselectivity.

show abstract

Recent Advances in Chiral Resolution Through Membrane‐Based Approaches

Abstract: For Abstract see ChemInform Abstract in Full Text.

Cited by 8 publications

References 1 publication

Enzymatic membrane reactors: the determining factors in two separate phase operations

Enzymatic membrane reactors: the determining factors in two separate phase operations

Keratinous Materials as Novel Absorbent Systems for Toxic Pollutants

Electrospun nanofiber membranes from polysulfones with chiral selector aimed for optical resolution

Contact Info

Product

Resources

About