Recent advances in controlled manipulation of micro/nano particles: a review

Abstract

This review discusses the transformative impact of micro/nano particle manipulation techniques across scientific and technological disciplines. Emphasizing the pivotal role of precise control at the micro and nanoscale, the paper categorizes manipulation strategies into mechanical/surface force-based, field-control manipulation, and microfluidics manipulation. It addresses challenges specific to the submicrometer scale, highlighting the strengths and limitations of each approach. The unique behaviors exhibited by objects at the micro–nano scale influence the design and operation of manipulators, algorithms, and control systems, particularly in interactions with biological systems. The review covers dielectrophoresis and magnetic manipulation, showcasing their applications in particle manipulation and microfluidics. The evolution of optical tweezers, including holographic, surface plasmon-based, and optical fiber tweezers, is discussed, emphasizing their contributions in various scientific fields. Additionally, the paper also explores the manipulation of micro/nano particle in microfluidic platforms. The comprehensive review underscores the significance of understanding manipulation strategies in diverse environments, anticipating further advancements in science and technology.