Recent Advances in Dual Triplet Ketone/Transition-Metal Catalysis

Abstract

Dual light-excited ketone/transition-metal catalysis is a rapidly developing field of photochemistry. It allows for versatile functionalizations of C–H or C–X bonds enabled by triplet ketone acting as a hydrogen-atom-abstracting agent, a single-electron acceptor, or a photosensitizer. This review summarizes recent developments of synthetically useful transformations promoted by the synergy between triplet ketone and transition-metal catalysis.1 Introduction2 Triplet Ketone Catalysis via Hydrogen Atom Transfer2.1 Triplet Ketones with Nickel Catalysis2.2 Triplet Ketones with Copper Catalysis2.3 Triplet Ketones with Other Transition-Metal Catalysis3 Triplet Ketone Catalysis via Single-Electron Transfer4 Triplet Ketone Catalysis via Energy Transfer5 Conclusions

Cluster Preface: Special Issue Honoring Masahiro Murakami’s Contributions to Science

“…36 Gevorgyan summarizes the potential of dual triplet ketone and transition-metal catalysis as a new platform for forging sp 3 architectures by harnessing the propensity of multifaceted triplet ketones for enabling both hydrogen-atom transfer and single-electron transfer. 37 Meanwhile Kanai discusses the advances made in the context of catalytic dehydrogenation of saturated N-heterocycles, aliphatic alcohols and even the most problematic hydrocarbons. 38 Finally, Loh summarizes recent techniques aimed at promoting catalyst-free biocompatible reactions such as Mukaiyama reactions, click processes and applications on the functionalization of proteins.…”