2024
DOI: 10.1111/cbdd.14638
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Recent Advances in Medicinal Chemistry of Memantine Against Alzheimer's Disease

Yash Pal Singh,
Harish Kumar

Abstract: Alzheimer's disease (AD) is a chronic progressive, age‐related neurodegenerative brain disorder characterized by the irreversible decline of memory and other cognitive functions. It is one of the major health threat of the 21st century, which affects around 60% of the population over the age of 60 years. The problem of this disease is even more major because the existing pharmacotherapies only provide symptomatic relief without addressing the basic factors of the disease. It is characterized by the extracellul… Show more

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