2024
DOI: 10.1002/adhm.202401295
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Recent Advances in Microfluidics for Nucleic Acid Analysis of Small Extracellular Vesicles in Cancer

Sareh Zhand,
Dale Mark Goss,
Yuen Yee Cheng
et al.

Abstract: Small extracellular vesicles (sEVs) are membranous vesicles released from cellular structures through plasma membrane budding. These vesicles contain cellular components such as proteins, lipids, mRNAs, microRNAs, long‐noncoding RNA, circular RNA, and double‐stranded DNA, originating from the cells they are shed from. Ranging in size from ≈25 to 300 nm and play critical roles in facilitating cell‐to‐cell communication by transporting signaling molecules. The discovery of sEVs in bodily fluids and their involve… Show more

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