Recent advances in surface‐enhanced Raman scattering‐based sensors for the detection of inorganic ions: Sensing mechanism and beyond

Abstract

Inorganic ions determination has been receiving increased attention due to its strong environmental and biomedical impact. Surface‐enhanced Raman scattering (SERS) spectroscopy has been considered to be a promising alternative method for inorganic ions analysis. Initially, the detection of inorganic ions is indirectly achieved by monitoring the SERS spectral alteration of a molecular probe (Raman reporter) upon its interaction with a specific inorganic ion. Recent years, based on incorporation of a functional molecule, an aptamer, and a nanocatalyst into a sensing system, numerous new methods have been proposed for the construction of sensitive SERS‐based inorganic ion sensors. Herein, this review is devoted to the recent advances in SERS‐based sensors for the determination of inorganic ions and specially focuses on the sensing mechanism and sensing methods. In addition, the current challenges and future research opportunities in utilizing SERS‐based methods for inorganic ions sensing are briefly featured.

Physico-Chemical Properties of Inorganic NPs Influence the Absorption Rate of Aquatic Mosses Reducing Cytotoxicity on Intestinal Epithelial Barrier Model

“…The widespread use of inorganic nanomaterials, namely, metal (Ag NPs and Au NPs) and metal oxide NPs (SiO 2 NPs and TiO 2 NPs) in a broad range of commercial products [ 1 ], such as paints [ 2 ], cosmetics [ 3 ], medicine [ 4 , 5 ], sensors [ 6 , 7 ], food additives [ 8 , 9 , 10 ], and sunscreens [ 11 , 12 ], highlighted the problem of their behavior and fate in several environmental compartments [ 13 ]. The unique physico-chemical properties, due to the high surface-to-volume ratio, make NPs very reactive materials with respect to the bulk counterpart [ 14 , 15 ].…”

Human metabolite detection by surface-enhanced Raman spectroscopy

“…Despite the fact that indirect SERS has been widely used for detecting macro biomolecules and cells [ [81] , [82] , [83] ], the detection of metabolites, however, is commonly applied in a direct way. This can be attributed to two reasons.…”

Preface to the special issue dedicated to Professor Richard P. Van Duyne (1945–2019)

“…In addition, the review briefly introduces current challenges and future research opportunities for SERS in inorganic ion sensing. [ 21 ]…”

“…In addition, the review briefly introduces current challenges and future research opportunities for SERS in inorganic ion sensing. [21] Haynes et al provide a systematic investigation of how the three major metal film over nanosphere (FON) substrate fabrication parameters-nanosphere size, deposited metal thickness, and metal choice-impact the resulting LSPR. They employ optimized FONs for the sensing of an important allergen, soybean agglutinin with a limit of detection of 10 μg/ml.…”