Recent advances in the antilung cancer activity of biosynthesized gold nanoparticles

Wang, Yadong; Xu, Jie; Shi, Li; Yang, Haiyan

doi:10.1002/jcp.29789

Cited by 15 publications

(2 citation statements)

References 48 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The enthusiasm in synthesis, characterization and silver nanoparticles application has grown rapidly against a broad spectrum of microorganisms (36,41) and have a considerably low propensity to activate microbial resistance in comparison to antibiotics (42). For the synthesis of nanoparticles basically, two major paths are followed; these are the top-down and bottom-up approach.…”

Section: Silver Nanoparticles Synthesismentioning

confidence: 99%

Synthesis and Antibacterial Activity of Silver Nanoparticles: Systematic Review

Thakur

2024

IJSREM

View full text Add to dashboard Cite

Silver is exploited for the benefit of mankind from past centuries. Silver has been proved to be much more powerful when compared to other metallic nanoparticles, not only bactericidal properties but it is also effective against eukaryotic microorganisms and viruses. Creation of Ag Nanoparticles has increased the silver efficacy many folds due to their physical and chemical properties, especially the surface area to volume ratio is most important imparting the antibacterial activity over various microorganisms. To lessen bacterial infections in incurable wounds nanocrystalline silver dressings, creams, gels are formulated. However, several problems are associated with the use. Silver nanoparticle toxicity is a major threat associated with their use and the inhibition of beneficiary microorganisms due to lack of specificity of silver nanoparticles is environmentalist’s concern. To reduce the threats associated, there should be a careful assessment of the silver nanoparticles release into the environment and should be regulated. It has to be noted that novel methods to produce silver nanoparticles which reduce the toxicity and other associated threats has to be developed in the future to exploit the vast capabilities of the silver nanoparticles for the benefit of mankind. As technology advancement is always in demand with changing environmental conditions, the present review will focus on the synthesis and antibacterial properties of silver nanoparticles along with its environmental impact. Key Words: Silver nanoparticles ∙ Antibacterial Activity ∙ Microorganisms ∙ Environmental Impact

show abstract

Section: Silver Nanoparticles Synthesismentioning

confidence: 99%

Synthesis and Antibacterial Activity of Silver Nanoparticles: Systematic Review

Thakur

2024

IJSREM

View full text Add to dashboard Cite

show abstract

“…AuNPs are emerging as novel radiosensitizers for cancer patients because of their synthetic versatility, unique chemical, electronic, and optical properties, and high X-ray absorption [6] . AuNPs have been documented to exert anti-oncogenic activity in lung cancer [7] . More importantly, AuNPs are widely recognized to be a comparatively reliable small interfering RNA (siRNA) delivery strategy due to their biocompatibility and capacity to protect siRNA against degradation and versatility offered by their tunable shape, size and optical properties [8] .…”

Section: Introductionmentioning

confidence: 99%

Radiosensitizing effect of gold nanoparticle loaded with small interfering RNA-SP1 on lung cancer

Zhou¹,

Jiang²,

Gu³

et al. 2021

Translational Oncology

View full text Add to dashboard Cite

Highlights siRNA-SP1-loaded AuNPs (AuNPs-si-SP1) inhibits SP1 expression in lung cancer cells. GZMB expression is elevated by silencing SP1 in lung cancer cells. AuNPs-si-SP1 combined with radiotherapy inhibits lung cancer growth effectively. AuNPs-si-SP1 enhances radiosensitivity of lung cancer via SP1/GZMB axis. AuNPs-si-SP1 provides a novel target for radiotherapy of lung cancer.

show abstract