Recent Advances in the Colorimetric Detection of Cyanide

Abstract

This short-review discusses the recent developments in the colorimetric detection of cyanide with different types of receptors. Significant progress in terms of selectivity, sensitivity and straightforwardness has been observed for either organic-, main group- or transition metal-based sensors. Our group has developed a simple and highly specific system for the optical sensing of cyanide based on the conformational switch of commercially available vitamin B12.

A novel glycoconjugated N-acetylamino aldehyde hydrazone azo dye as chromogenic probe for cyanide detection in water

“…In the case of azo dye 6, its treatment with selected anions such as CN − , F − , AcO − , and H 2 PO 4 2− in DMSO, both cyanide and fluoride anions exhibited color change from colorless to light purple and to light yellow, respectively (Fig. 1, left).…”

“…Stock solutions (1 mM) of the tetrabutylammonium salts of (CN − , F − , AcO − , S 2− , PO 4 3− , HSO 4 − , CO 3 2− and H 2 PO 4 − ) in water were prepared. Stock solutions of chemodosimeter (0.1 mM) were prepared in water.…”

“…The extreme toxicity of cyanide anions in physiological [1,2] as well as environmental [3] systems has led many researchers to develop colorimetric probes [4,5] for the sensitive and selective detection of cyanide. In the last years, colorimetric probes for naked eye detection have attracted considerable interest for their simple and fast implementation as well as their high sensitivity.…”

Identification of Diastereomeric Cyano–Aqua Cobinamides with a Backbone‐Modified Vitamin B12 Derivative and with 1H NMR Spectroscopy

“…[3,4] Recently, "incomplete" corrinoids have regained considerable attention as biologically inspired catalysts [5][6][7] as well as chemosensors for the straightforward detection of cyanide ( Figure 1). [8][9][10] Enormous effort has been devoted by Friedrich et al to characterize axial diastereomers of cyano-aqua Cbi. [11][12][13] In other important studies, Brown et al assigned, by heteronuclear NMR spectroscopy, the α-(lower side) and β-(upper side) positions of various Cbi with the help of chemically enriched axial ligands and the corresponding Cbl analogues.…”

Rapid visual detection of blood cyanide

“…Many chemosensors have been recently developed for the detection of cyanide, [25][26][27][28] but only a few work in biological samples.…”