Recent advances in the design of organic photothermal agents for cancer treatment: A review

Lee, Seongman; Min, Suhong; Kim, Gahyun; Lee, Songyi

doi:10.1016/j.ccr.2024.215719

“…13 BODIPY derivatives possess many ideal photosensitizer (PS) features, which makes them useful agents in photodynamic therapy (PDT), 14 and, more recently, in photothermal therapy (PTT). 15 They have also been used in optoelectronic devices, including organic light-emitting diodes (OLEDs) 16 and organic photovoltaics (OPVs). 17 Derivatives of BODIPY are frequently used in biological imaging.…”

Section: Introductionmentioning

confidence: 99%

Chemoselective reaction of methoxyaminomethyl BODIPYs with unprotected carbohydrates: a powerful tool for accessing BODIPY neoglycosides

Gómez,

García-Fernández,

Santana

et al. 2024

Org. Chem. Front.

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Photon‐Driven Dye Induction Pyroptosis: An Emerging Anti‐Tumor Immunotherapy Paradigm

Zeng,

Wang,

Kang

et al. 2024

Angewandte Chemie

0

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Photoimmunotherapy represents a novel and promising modality in anti‐tumor immunotherapy, offering new hope in the realm of cancer treatment due to its distinctive mechanism and substantial therapeutic efficacy. This innovative approach synergistically integrates photon technology with immunological principles, utilizing photon energy to activate the body's immune response. Photon‐driven pyroptosis, a pivotal element of photoimmunotherapy, has significantly revitalized the advancement of this discipline. To support this critical progress, this review offers an exhaustive examination of the organic dyes presently employed for photon‐driven pyroptosis, alongside an analysis of the prevailing challenges and opportunities in dye molecule design. It is our aspiration that this minireview will contribute to the acceleration of developments in photon‐driven pyroptosis dye and the broader field of photoimmunotherapy.

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Photon‐Driven Dye Induction Pyroptosis: An Emerging Anti‐Tumor Immunotherapy Paradigm

Zeng,

Wang,

Kang

et al. 2024

Angew Chem Int Ed

0

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Photoimmunotherapy represents a novel and promising modality in anti‐tumor immunotherapy, offering new hope in the realm of cancer treatment due to its distinctive mechanism and substantial therapeutic efficacy. This innovative approach synergistically integrates photon technology with immunological principles, utilizing photon energy to activate the body's immune response. Photon‐driven pyroptosis, a pivotal element of photoimmunotherapy, has significantly revitalized the advancement of this discipline. To support this critical progress, this review offers an exhaustive examination of the organic dyes presently employed for photon‐driven pyroptosis, alongside an analysis of the prevailing challenges and opportunities in dye molecule design. It is our aspiration that this minireview will contribute to the acceleration of developments in photon‐driven pyroptosis dye and the broader field of photoimmunotherapy.

show abstract

Recent advances in the design of organic photothermal agents for cancer treatment: A review

Cited by 7 publications

References 234 publications

Chemoselective reaction of methoxyaminomethyl BODIPYs with unprotected carbohydrates: a powerful tool for accessing BODIPY neoglycosides

Chemoselective reaction of methoxyaminomethyl BODIPYs with unprotected carbohydrates: a powerful tool for accessing BODIPY neoglycosides

Photon‐Driven Dye Induction Pyroptosis: An Emerging Anti‐Tumor Immunotherapy Paradigm

Photon‐Driven Dye Induction Pyroptosis: An Emerging Anti‐Tumor Immunotherapy Paradigm

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