2023
DOI: 10.1016/j.jddst.2023.104539
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Recent advances in the preventative strategies for postoperative adhesions using biomaterial-based membranes and micro/nano-drug delivery systems

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Cited by 7 publications
(3 citation statements)
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“…2−5 Biomaterials in various physical forms, capable of physically isolating the wound tissues, have attracted significant interest, 3,6,7 but several problems remain open due to the complexity of the causes of postoperative adhesion, and the antiadhesive barriers prepared under the guidance of straightforward mechanisms are insufficient to fulfill the diverse clinical needs. 2,5 Safe and efficacious strategies for the clinical prevention of postoperative adhesion are still urgently needed.…”
Section: Introductionmentioning
confidence: 99%
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“…2−5 Biomaterials in various physical forms, capable of physically isolating the wound tissues, have attracted significant interest, 3,6,7 but several problems remain open due to the complexity of the causes of postoperative adhesion, and the antiadhesive barriers prepared under the guidance of straightforward mechanisms are insufficient to fulfill the diverse clinical needs. 2,5 Safe and efficacious strategies for the clinical prevention of postoperative adhesion are still urgently needed.…”
Section: Introductionmentioning
confidence: 99%
“…Consequently, there is much interest in the treatment of postoperative adhesion. To date, several strategies have been developed to relieve postoperative adhesion, such as implementing physical barriers, administering pharmacological agents locally or systemically, or a combination of the two. Biomaterials in various physical forms, capable of physically isolating the wound tissues, have attracted significant interest, ,, but several problems remain open due to the complexity of the causes of postoperative adhesion, and the antiadhesive barriers prepared under the guidance of straightforward mechanisms are insufficient to fulfill the diverse clinical needs. , Safe and efficacious strategies for the clinical prevention of postoperative adhesion are still urgently needed.…”
Section: Introductionmentioning
confidence: 99%
“…The fluid is safe in combination with intestinal sutures, but it interferes with postoperative CT imaging due to the large amount of free fluid. Therefore, surgeons are somewhat wary of using these products on intestinal sutures, especially in sutures with an increased risk of leakage or in cases of massive contamination [14][15][16][17][18][19].…”
Section: Introductionmentioning
confidence: 99%