Recent Advances in the Synthesis of Pyrrolidines

Abstract

The pyrrolidine ring is one of the important and valuable heterocyclic compounds. This five-membered ring containing nitrogen is also known as tetrahydropyrrole. This heterocyclic scaffold is present in medicinal and biological molecules as well as bioactive compounds and alkaloids because of the properties and characteristics of this ring. Considering the sensitivity of the subject and the importance of this structure, the recent advances in the synthesis of these types of structures are very important. In this chapter, we reviewed the recent advances in the synthesis of pyrrolidines along with the mechanisms and limitations, with a detailed discussion from 2019 to 2023.