Recent advances in the synthesis of quinolines: a review

Abstract

This review article gives information about the recent advances in the synthesis of quinoline derivatives by various eco-friendly, green and clean protocols.

The Beneficial Sinergy of MW Irradiation and Ionic Liquids in Catalysis of Organic Reactions

“…Thus, it is not surprising that the synthesis of key rings has been explored in terms of sustainability, as well illustrated in 2014 reviews discussing alternative reaction methods for the synthesis of quinoline [127] and benzothiazole [128] derivatives, including syntheses promoted by microwave or ultrasound, recyclable and reusable catalysts, non-volatile solvents as ILs, or solvent-free conditions.…”

Convergent Synthesis of 2-Aryl-Substituted Quinolines by Gold-Catalyzed Cascade Reaction

“…[5][6][7] Therefore, quinoline compounds have inspired the development of new synthetic methods 8,9) for the formation of the N-heterocyclic scaffold due to their potential utility in the pharmaceutical industry. As classical and conventional synthetic methods, the Skraup,10) Doebner and von Miller, 11) Combes, 12) Friedländer, 13) and Pfitzinger 14) quinoline syntheses are well known; however, these methods often encounter problems with functional group compatibility as they require strong acidic or basic conditions.…”

Synthesis and <i>In Vitro</i> Antibacterial and Antifungal Evaluation of Quinoline Analogue Azetidin and Thiazolidin Derivatives

“…Volume 39 Quinolines could be synthesized using various methodologies and recently we have reported one review article on it [33]. Due to the environmental pollution, we have tried to carry out all the transformations using green chemistry principle.…”