Recent developments in bisdiborane chemistry: BCB, BCCB, BCCB and BCCB compounds

Abstract

An overview of the development of new strategies in organic synthesis with a minimum of chemical steps is becoming increasingly necessary for the efficient assembly of complex molecular structures. Therefore, the combination of multiple reactions in a single operation represents a particularly efficient approach. Among these strategies, the synthesis and reactivity of bisdiboranes has never been reviewed although its popularity for the synthesis of complex architectural molecules has been steadily increasing during the last decade. This review is intended to highlight the use of partly geminated boranes (B-C-B), and also bisdiborane reagents (B-C-C-B, B-C C-B, B-C C-B).

Recent Advances in the Addition of Amide/Sulfonamide Bonds to Alkynes

“…The addition of atom–atom bonds to alkynes has become an important strategy for the functionalization of carbon–carbon triple bonds [1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16]. These intermolecular and intramolecular addition reactions provide a facile and efficient access to highly functionalized alkenes and cyclic compounds, respectively, in a high atom- and step-economic manner.…”

Polyborylated reagents for modern organic synthesis

“…This review focuses on not only gem -diboryl but also vic -diboryl compounds illustrated in Figure 1 and summarizes the preparations and selective transformations for organic synthesis. 9 )…”

Copper‐Catalyzed Borylation Reactions of Alkynes and Arynes

“…On the other hand, installation of both boryl moieties of a diboron compound into the product, that is, diborylation, [3,4] is also of high synthetic significance, since the resulting two C À B bonds can both be utilized for the synthesis of complex molecules by Suzuki-Miyaura coupling and other methods. [5] However, potential copper catalysis for diborylation reactions remains to be exploited. [6] Herein, we report the first diborylation of unsaturated carbon linkages by copper catalysis; the broad substrate scope makes this a universal method for the synthesis of vic-diborylalkenes (from alkynes) and vic-diborylarenes (from arynes), furthermore, this method is more practical and economical than that with the well-known catalytic system based on platinum.…”