Recent developments in research of trauma and personality disorders

Yen, Shirley; Shea, M. Tracie

doi:10.1007/s11920-001-0073-3

Cited by 7 publications

(3 citation statements)

References 48 publications

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“…Major Depressive Disorder (MDD) or depressive symptoms, which many of the included studies did not adjust for, may explain the strong association observed with external causes of death, as suicidality risk is increased combined with PTSD [ 77 ]. Adjusting for psychiatric disorders in a study investigating PTSD as an exposure is a challenge, as other conditions may also share trauma as a common aetiology [ 78 ]. However, adjusting for these factors may be unnecessary in the possibility that PTSD may precipitate the formation of other psychiatric disorders, leading to subsequent mortality.…”

Section: Discussionmentioning

confidence: 99%

Lifetime posttraumatic stress disorder as a predictor of mortality: a systematic review and meta-analysis

et al. 2023

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Background Posttraumatic Stress Disorder (PTSD) could potentially increase the risk of mortality, and there is a need for a meta-analysis to quantify this association. This study aims to determine the extent to which PTSD is a predictor of mortality. Methods EMBASE, MEDLINE, and PsycINFO were searched systematically on 12th February 2020, with updated searches conducted in July 2021, and December 2022 (PROSPERO CRD42019142971). Studies involving community-dwelling participants with a diagnosis of PTSD or PTSD symptoms, and a comparator group of individuals without PTSD, and which assessed mortality risk, were included. A random-effects meta-analysis was conducted on studies reporting Odds Ratio (OR), Hazard Ratio (HR), and Risk Ratio (RR), and subgroup analysis was also performed by age, sex, type of trauma experienced, PTSD diagnosis, and cause of death. Results A total of 30 eligible studies of mostly good methodological quality were identified, with a total of more than 2.1 million participants with PTSD. The majority of studies involved male-dominated, veteran populations. PTSD was associated with a 47% (95% CI: 1.06–2.04) greater risk of mortality across six studies that reported OR/RR, and a 32% increased risk across 18 studies which reported time to death (HR: 1.32, 95% CI: 1.10–1.59). There was very high study heterogeneity (I2 > 94%) and this was not explained by the prespecified subgroup analysis. Conclusion PTSD is associated with increased mortality risk, however further research is required amongst civilians, involving women, and in individuals from underdeveloped countries.

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Section: Discussionmentioning

confidence: 99%

Lifetime posttraumatic stress disorder as a predictor of mortality: a systematic review and meta-analysis

et al. 2023

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“…Une incidence plus élevée de carences, de négligences et d'abus dont sexuels durant l'enfance des sujets TPL supporte un scénario de développement psychologique compromis (Zanarini et Frankenburg, 1997 ;Van den Bosch et al, 2002 ;Yen et al, 2001 ;Simeon et al, 2003). Ces traumatismes répétés faciliteraient l'éclosion potentielle du TSPT (Breslau et al, 1991).…”

Section: Dissociation Et Trouble De Personnalité Limiteunclassified

“…Il y aurait une association de cause à effet entre abus sexuel et TPL mais aucune relation causale prouvée ni d'association spécifique entre traumatisme et trouble de personnalité (Links et al, 1988 ;Zanarini et al, 1989 ;Paris et al, 1994 ;Timmerman et Emmelkamp, 2001 ;Yen et Shea, 2001 ;Goodman et al, 2003 ;Ball et Links, 2009). Une autre hypothèse sur l'étiologie du TPL réside dans la négligence, la carence par l'absence de soins, moins sensationnaliste ou facile à définir mais encore plus dévastatrice (Simeon et al, 2003).…”

Section: Dissociation Et Trouble De Personnalité Limiteunclassified

Comprendre la dissociation chez les patients avec un trouble de personnalité limite

Renaud

2011

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Cet article examine la dissociation, un concept psychiatrique controversé qui se rencontre dans le quotidien du clinicien. À partir d’une recherche sur Pubmed/Ovid avec les mots clés dissociation et trouble de personnalité limite et d’autres références, l’auteure décrit le phénomène dissociatif dans ses aspects cliniques chez les sujets atteints du trouble de personnalité limite (TPL). L’article discute des hypothèses psychodynamiques et des données neurophysiologiques pour expliquer la dissociation. Certains validateurs neurophysiologiques et neuro-anatomiques produits grâce à l’imagerie cérébrale, et des études du métabolisme de neurotransmetteurs sont étudiés pour étayer les énoncés hypothétiques. L’auteure conclut sur un modèle de mécanisme de défense dans un contexte de prédisposition biologique, de carence du développement psychologique ou d’une sensibilisation post-traumatique et suggère des pistes thérapeutiques.Dissociation is a disturbing psychiatric concept fraught with controversy. It is however encountered in clinical contexts and has to be understood by clinicians. This article based on a Pubmed/Ovid on line research with key words dissociation and borderline personality disorder and other references, describes the clinical aspects of the dissociative phenomena in patients with borderline personality disorder. Psychodynamic hypotheses and neurophysiological data are examined to explain dissociation. Neurophysiological and neuroanatomical variables provided by cerebral imagery controlled studies support hypotheses brought forward. The article concludes with a defence mechanism developed within a context of biological predisposition, deprived psychological development and in reaction to trauma. In conclusion, emerging psychotherapeutic solutions are summarized.Este artículo examina la disociación, concepto psiquiátrico controversial, con la que el clínico se encuentra cotidianamente. A partir de una búsqueda en Pubmed/Ovid con las palabras clave disociación y trastorno de la personalidad límite y otras referencias, la autora describe el fenómeno disociativo, en sus aspectos clínicos, en las personas que sufren de un trastorno de la personalidad límite (TPL). El artículo discute las hipótesis psicodinámicas y los datos neurofisiológicos para explicar la disociación. Se estudian ciertos validadores neurofisiológicos y neuroanatómicos producidos gracias a neuroimágenes, así como estudios del metabolismo de neurotransmisores, con el fin de apoyar los enunciados hipotéticos. La autora concluye con un modelo de mecanismo de defensa en un contexto de predisposición biológica, de carencia del desarrollo psicológico o de una sensibilización postraumática, y sugiere pistas terapéuticas.Este artigo examina a dissociação, um conceito psiquiátrico controverso que encontra-se no cotidiano do clínico. A partir de uma pesquisa sobre o Pubmed/Ovid com as palavras-chave dissociação e transtorno de personalidade limite e outras referências, a autora descreve o fenômeno dissociativo em seus aspectos clínicos nos paciente...

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Common and distinct patterns of gray matter alterations in borderline personality disorder and posttraumatic stress disorder: A dual meta-analysis

Lou

Sun

Cui

et al. 2021

Neuroscience Letters

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Recent developments in research of trauma and personality disorders

Cited by 7 publications

References 48 publications

Lifetime posttraumatic stress disorder as a predictor of mortality: a systematic review and meta-analysis

Lifetime posttraumatic stress disorder as a predictor of mortality: a systematic review and meta-analysis

Comprendre la dissociation chez les patients avec un trouble de personnalité limite

Common and distinct patterns of gray matter alterations in borderline personality disorder and posttraumatic stress disorder: A dual meta-analysis

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