Recent Developments of Carboxymethyl Cellulose

Abstract

Carboxymethyl cellulose (CMC) is one of the most promising cellulose derivatives. Due to its characteristic surface properties, mechanical strength, tunable hydrophilicity, viscous properties, availability and abundance of raw materials, low-cost synthesis process, and likewise many contrasting aspects, it is now widely used in various advanced application fields, for example, food, paper, textile, and pharmaceutical industries, biomedical engineering, wastewater treatment, energy production, and storage energy production, and storage and so on. Many research articles have been reported on CMC, depending on their sources and application fields. Thus, a comprehensive and well-organized review is in great demand that can provide an up-to-date and in-depth review on CMC. Herein, this review aims to provide compact information of the synthesis to the advanced applications of this material in various fields. Finally, this article covers the insights of future CMC research that could guide researchers working in this prominent field.

Biocompatible and Biomaterials Application in Drug Delivery System in Oral Cavity

“…Meanwhile, some patients have the risk of allergic cross-reactions to chitosan or other dental varnishes because of seafood allergy or other allergic conditions to chitosan or other antimicrobial vehicles. Therefore alternative selection for transport drugs is carboxymethylcellulose, which can prohibit activation of Streptococcus mutans , simultaneously transport drugs to aimed receptors and present antimicrobial activity [ 45 , 46 ].…”

Cellulosic Polymers for Enhancing Drug Bioavailability in Ocular Drug Delivery Systems

“…By β-1,4-glycosidic bonds the polysaccharide repeating units are connected. CMC differs from cellulose as CMC has anionic carboxymethyl groups (CH 2 COOH), which are replaced by the hydrogen atom of a hydroxyl group of cellulose and it was first synthesized in 1918 but the commercial preparation was developed in 1920 in Germany [176]. Cellulose precursors are corn cob [177], corn stalk [178], corn husk [179], durian rind [180], maize stalks, pineapple peel [181], orange peels, sugarcane bagasse [182], asparagus stalk [183], and other materials such as waste paper [184], waste textile [185], knitted rag [186], cotton gin waste [187], waste cotton linter, etc.…”

Disposable Food Packaging and Serving Materials—Trends and Biodegradability

“…Transparent films by industrial cellulose pulp solubilization in tetramethylguanidine-based ionic liquids were investigated by Ribeiro et al [ 77 ]. Carboxymethyl cellulose, an ionic, water-soluble derivative of cellulose, is one of the most promising cellulose derivatives, characterized by good surface properties, mechanical strength, tunable hydrophilicity, viscous properties, availability, and low-cost synthesis process [ 78 ]. It is used in various fields such as food, paper, textile, and pharmaceutical industries.…”