Recent developments of monolithic and open‐tubular capillary electrochromatography (2017–2019)

Hu, Linfeng; Yin, Shou-Wei; Zhang, Hao; Yang, Feng‐Qing

doi:10.1002/jssc.201901168

Cited by 40 publications

(19 citation statements)

References 129 publications

(146 reference statements)

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“…CEC did not become a widely used method for peptide separations and analyses. Recent advances of CEC performed in three modes, that is, in packed, monolithic, and open‐tubular (OT) columns, are presented in general reviews on CEC [139], monolithic CEC [140], and open‐tubular CEC (OT‐CEC) [141]. They mostly deal with new stationary phases, such as microporous materials (MOFs, covalent organic frameworks, porous organic cages, and knitted aromatic polymers, nanoparticles, polymer materials, silica‐based materials, and biomaterials).…”

Section: Separations By the Particular Ce And Cec Methodsmentioning

confidence: 99%

Recent developments in capillary and microchip electroseparations of peptides (2019–mid 2021)

Kašička

2021

Electrophoresis

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The review provides a comprehensive overview of developments and applications of high performance capillary and microchip electroseparation methods (zone electrophoresis, isotachophoresis, isoelectric focusing, affinity electrophoresis, electrokinetic chromatography, and electrochromatography) for analysis, microscale isolation, and physicochemical characterization of peptides from 2019 up to approximately the middle of 2021. Advances in the investigation of electromigration properties of peptides and in the methodology of their analysis, such as sample preparation, sorption suppression, EOF control, and detection, are presented. New developments in the individual CE and CEC methods are demonstrated and several types of their applications are shown. They include qualitative and quantitative analysis, determination in complex biomatrices, monitoring of chemical and enzymatic reactions and physicochemical changes, amino acid, sequence, and chiral analyses, and peptide mapping of proteins. In addition, micropreparative separations and determination of significant physicochemical parameters of peptides by CE and CEC methods are described.

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Section: Separations By the Particular Ce And Cec Methodsmentioning

confidence: 99%

Recent developments in capillary and microchip electroseparations of peptides (2019–mid 2021)

Kašička

2021

Electrophoresis

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“…Other operating modes are Capillary Electrochromatography and MEKC. In Capillary Electrochromatography, a stationary phase fills the capillary so making it possible to combine the separation driven by a stationary phase together with adjunctive resolution power provided by a high electrical voltage [91][92][93]. With MEKC, it is possible to separate two neutral species by means of micelles created by a surfactant added to the solution [94].…”

Section: Capillary Electrophoresismentioning

confidence: 99%

Authenticity assessment of dairy products by capillary electrophoresis

et al. 2021

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Authenticity assessment of dairy products by capillary electrophoresisMilk and derivatives are a very important part in the diet of the world population. Products from goat, buffalo, and sheep species have a greater economic value than the cow ones, therefore, authenticity frauds by improperly adding cow's milk occur frequently: dairy products are among the seven more attractive foods for adulteration. Milk from each of the above-cited animal species has its own definite profile of whey proteins (variants of α-lactalbumin and β-lactoglobulin) and its definite profile of caseins (variants of α S1 -, α S2 -, β-, and κ-casein). Such proteins can be usefully exploited as markers of authenticity by using capillary electrophoresis which is the technique of choice for the analysis of proteins. Due to the multiple adjustable parameters that are unknown to other analytical techniques, capillary electrophoresis is able to detect frauds in milk mixtures and cheese with little use of solvents, fast analysis time, and ease of operation. This makes it attractive and competitive for routine checks that are very important to fight the adulteration market. Advantages and limitations are discussed.

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“…It relies on the application of a high voltage, responsible for the generation of an EOF and transportation of analytes and mobile phase to the detector. The high efficiency can be partly ascribed to the flat flow profile of the EOF [5,7,8]. For an in-depth study of the history, potential, advantages, and disadvantages of the CEC, a recent review article, reporting various separations in the field of chiral analysis, could be consulted [9].…”

Section: Capillary Electromigration Techniquesmentioning

confidence: 99%

Potentiality of miniaturized techniques for the analysis of drugs of abuse

et al. 2021

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Capillary electromigration (CE) and liquid chromatographic techniques (CLC/nano‐LC) are miniaturized techniques offering distinct advantages over conventional ones in the field of separation science. Among these, high efficiency, high chromatographic resolution, and use of minute volumes of both mobile phase and sample volumes are the most important. CE and CLC/nano‐LC have been applied to the analysis of many compounds including peptides, proteins, drugs, enantiomers, ions, etc. Over the years, the methods described here have also been used for the analysis of compounds of clinical, forensic, and toxicological interest. In this review article, the main features of the mentioned techniques are summarized. Their potentiality for the analysis of drugs of abuse are discussed. Some selected applications in this field in the period of 2015–present are also reported.

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Recent developments of monolithic and open‐tubular capillary electrochromatography (2017–2019)

Cited by 40 publications

References 129 publications

Recent developments in capillary and microchip electroseparations of peptides (2019–mid 2021)

Recent developments in capillary and microchip electroseparations of peptides (2019–mid 2021)

Authenticity assessment of dairy products by capillary electrophoresis

Potentiality of miniaturized techniques for the analysis of drugs of abuse

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