Recent innovations in the screening and diagnosis of systemic sclerosis-associated interstitial lung disease

Makol, Ashima; Nagaraja, Vivek; Amadi, Chiemezie C.; Pugashetti, Janelle Vu; Caoili, Elaine M.; Khanna, Dinesh

doi:10.1080/1744666x.2023.2198212

Cited by 6 publications

(1 citation statement)

References 109 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[4][5][6][7][8][9][10][11] ILD is one of the leading causes of death in SSc and RA, [12][13][14][15] and because of the high prevalence of ILD in SSc, all patients with SSc should be screened at the time of their diagnosis, even if they are asymptomatic. 16 Male African-American patients, patients positive for the anti-Scl-70 antibody, with diffuse cutaneous SSc subset, reflux/ dysphagia symptoms, and cardiac involvement, are at high risk for developing progressive ILD. 17 In patients with RA, ILD is the second leading cause of death after cardiovascular complications.…”

Section: Screening and Diagnosis For Interstitial Lung Disease In Sys...mentioning

confidence: 99%

Imaging Innovations in the Screening, Diagnosis, and Monitoring of Systemic Autoimmune Disease-Related Interstitial Lung Disease

Jokerst,

Yaddanapudi,

Chaudhary

et al. 2024

EMJ Radiol

Self Cite

View full text Add to dashboard Cite

Interstitial lung disease (ILD) is a common and serious complication of systemic autoimmune rheumatic diseases (SARD). The prevalence and prognosis of ILD vary depending on the type and severity of the underlying SARD. Recently, two drugs have been approved by the U.S. Food and Drug Administration (FDA) for the treatment of ILD in SARD, and the American College of Rheumatology (ACR) has issued guidelines for the screening and monitoring of these patients. Therefore, it is essential to detect and manage ILD in SARDs as early as possible. High-resolution CT of the chest is the current gold standard test for diagnosis of ILD, yet, it is not uniformly performed as an initial diagnostic test. This review discusses the latest advances in imaging techniques for the diagnosis, assessment, and follow-up of SARD-ILDs.

show abstract