Recent progress in the chemistry of bicyclic 6–6 systems: chemistry of pyrido[1,2-a]pyrimidines

Insights into the recent progress in the medicinal chemistry of pyranopyrimidine analogs

“…Thus, this study has been undertaken as a persistence of our previous programs and studies on highlighting the chemistry of heterocyclic compounds with miscellaneous biological activities and their significance in the fields of medicinal and pharmaceutical chemistry. [52][53][54][55][56][57][58][59] Our program deals with highlighting and exploring the prosperous medicinal chemistry of pyranopyrimidine compounds, particularly pyranoij2,3-d]pyrimidines, in the last five years. The topic of this research is an extension of our previous study that is interesting to highlight the recent methods and progress in the multicomponent synthesis of heterocycleincorporated pyranoij2,3-d]pyrimidine motif under different conditions.…”

Recent progress in the chemistry of β-aminoketones

“…This study is in continuation of our preceding plans and reports on emphasizing the chemistry of heterocycles with active moieties in the synthesis of heterocyclic compounds with varying biological activities and their impact in the elds of pharmaceutical and medicinal chemistry. [47][48][49][50][51][52][53][54][55][56][57][58][59][60][61] The literature survey deals with the scope of synthetic approaches applied for the synthesis of b-aminoketones and ascertaining their reactivity against reactions with diverse reagents.…”

Insights into the medicinal chemistry of heterocycles integrated with a pyrazolo[1,5-a]pyrimidine scaffold

“…48 On the other hand, the chemistry of bicyclic systems and their use in pharmaceutical and medicinal fields attracted researchers' interest in recent years. [49][50][51][52][53][54][55][56][57][58] A comprehensive study of the synthetic routes adopted to prepare pyrazoloij1,5a]pyrimidines has recently been published including all the synthetic courses from aminopyrazoles with different reagents or acyclic reactants under basic or acidic or mild conditions. 59 Also, other reviews discussed the protocols concerned for the synthesis of pyrazoloij1,5-a]pyrimidines with a non-comprehensive study.…”