Recent Purification Technologies and Human Health Risk Assessment of Microplastics

Park, Jun Woo; Lee, Su Jin; Hwang, Dae Youn; Seo, Sungbaek

doi:10.3390/ma13225196

Cited by 19 publications

(7 citation statements)

References 100 publications

(59 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Recently, MP were evaluated in various cells and animals, and determined as one of the risk factors for human health. However, conflicting results were reported for the toxicity of MP against human cells [ 4 ]. Most previous studies showed that MP induce some degree of toxicity or pathological changes in human cells, whereas few studies suggest no significant cellular toxicity, except at high concentrations [ 5 , 6 , 7 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

Novel Characterization of Constipation Phenotypes in ICR Mice Orally Administrated with Polystyrene Microplastics

Choi

Park

Kim

et al. 2021

IJMS

Self Cite

View full text Add to dashboard Cite

Indirect evidence has determined the possibility that microplastics (MP) induce constipation, although direct scientific proof for constipation induction in animals remains unclear. To investigate whether oral administration of polystyrene (PS)-MP causes constipation, an alteration in the constipation parameters and mechanisms was analyzed in ICR mice, treated with 0.5 μm PS-MP for 2 weeks. Significant alterations in water consumption, stool weight, stool water contents, and stool morphology were detected in MP treated ICR mice, as compared to Vehicle treated group. Also, the gastrointestinal (GI) motility and intestinal length were decreased, while the histopathological structure and cytological structure of the mid colon were remarkably altered in treated mice. Mice exposed to MP also showed a significant decrease in the GI hormone concentration, muscarinic acetylcholine receptors (mAChRs) expression, and their downstream signaling pathway. Subsequent to MP treatment, concentrations of chloride ion and expressions of its channel (CFTR and CIC-2) were decreased, whereas expressions of aquaporin (AQP)3 and 8 for water transportation were downregulated by activation of the mitogen-activated protein kinase (MAPK)/nuclear factor (NF)-κB signaling pathway. These results are the first to suggest that oral administration of PS-MP induces chronic constipation through the dysregulation of GI motility, mucin secretion, and chloride ion and water transportation in the mid colon.

show abstract

Section: Introductionmentioning

confidence: 99%

Novel Characterization of Constipation Phenotypes in ICR Mice Orally Administrated with Polystyrene Microplastics

Choi

Park

Kim

et al. 2021

IJMS

Self Cite

View full text Add to dashboard Cite

show abstract

“…Within the chemical method, we also have the technique of pyrolysis-gas chromatography/ pyrolysis-mass spectrometry (Pyr-GC-MS), which combines two methodologies with pyrolysis [65]. Another technique to consider for the identifcation of MPs is scanning electron microscopy (SEM) which provides high-resolution images using the area to be studied to reveal morphological details; this study is usually complemented by energy-dispersive Xray spectroscopy (EDS) which uses a high-energy electron beam to confrm the chemical composition of the particles, as each chemical element emits X-rays with specifc energies [66]. Apart from traditional methods, various novel techniques have been developed for the detection of MPs.…”

Section: Microplastic Identifcation Approachesmentioning

confidence: 99%

“…Tese techniques can be divided into physical, chemical, and biological methods, with each method having its own advantages and disadvantages based on the source of the particles to be removed. In this section, we will discuss the latest solutions in detail, including physical methods that use magnetic principles for water purifcation, such as the magnetic nanoparticle method [66].…”

Section: Emerging Techniques For the Removal Of Microplasticsmentioning

confidence: 99%

Microplastics in the Ecosystem: A Systematic Review of the Methods for Their Detection and Removal

Rubiños,

Grados,

Medina

et al. 2023

International Journal of Ecology

View full text Add to dashboard Cite

Currently, research on microplastics (MPs) has increased due to their rapid distribution throughout the world and their harmful effects on the ecosystem. However, a detailed description of their dispersion and the methods for both detection and removal has not been given. The objective of this research is to carry out a bibliographic review that allows for a multidisciplinary analysis of microplastic contamination and current detection and removal methods. The method used is PRISMA in which articles from reliable databases such as Scopus, Web of science, and Google Scholar were collected and analyzed to finally provide details on the physical and chemical methods for detecting MPs, in addition to presenting the technologies for their removal. As a result of the analysis, critical information was obtained from the different studies on the impact of MPs on the ecosystem and the variation in detection and removal efficiency according to the type of pretreatment and methods applied to the sample. It is concluded that this research is essential to understand the consequences that MPs have on the ecosystem and provide tools to evaluate and improve current technologies, mainly detection and removal.

show abstract

“…Most existing toxicity assessments have investigated the physical effects of microplastic particles. Physical and chemical effects of microplastics are not analyzed separately, and the results obtained from studies represent their overall toxicities . Therefore, dose–response assessments are unable to identify the driver(s) of toxicity: the physical effect of microplastics themselves or the chemicals associated with them.…”

Section: Introductionmentioning

confidence: 99%

Advancing Evaluation of Microplastics Thresholds to Inform Water Treatment Needs and Risks

Chowdhury,

Schmidt,

Anderson

et al. 2024

Environ. Health

View full text Add to dashboard Cite

Although human health impacts of microplastics are not well understood, concern regarding chemical contaminants retained on or within them is growing. Drinking water providers are increasingly asked about these risks, but strategies for evaluating them and the extent of treatment needed to manage them are currently lacking. Microplastics can potentially induce health effects if the concentration of contaminants adsorbed to them exceeds predetermined drinking water guidelines (e.g., Maximum Contaminant Levels). The risk posed by microplastics due to adsorbed contaminants is difficult to determine, but a worst-case scenario can be evaluated by using adsorption capacity. Here, a "Threshold Microplastics Concentration" (TMC) framework is developed to evaluate whether waterborne microplastic concentrations can potentially result in the intake of regulated contaminants on/in microplastics at levels of human health concern and identify treatment targets for managing associated health risk. Exceeding the TMC does not indicate an immediate health risk; it informs the need for detailed risk assessment or further treatment evaluation to ensure particle removal targets are achieved. Thus, the TMC concept and framework provide an updateable, science-based screening tool to determine if there is a need for detailed risk assessment or treatment modification due to waterborne microplastics in supplies used for potable water production.

show abstract

Recent Purification Technologies and Human Health Risk Assessment of Microplastics

Cited by 19 publications

References 100 publications

Novel Characterization of Constipation Phenotypes in ICR Mice Orally Administrated with Polystyrene Microplastics

Novel Characterization of Constipation Phenotypes in ICR Mice Orally Administrated with Polystyrene Microplastics

Microplastics in the Ecosystem: A Systematic Review of the Methods for Their Detection and Removal

Advancing Evaluation of Microplastics Thresholds to Inform Water Treatment Needs and Risks

Contact Info

Product

Resources

About