Recent strategic approach in postburn extremity scars and contractures

Karakol, Perçin; Bozkurt, Mehmet

doi:10.1080/2000656x.2020.1856670

Cited by 5 publications

(5 citation statements)

References 50 publications

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“…The therapeutic mechanism is that platelets can release brain-derived neurotrophic factor, vascular endothelial growth factor, and other growth factors after activation [ 26 , 27 ]. A large number of studies have proved that PRP can promote the regeneration of cartilage and bone tissue, as well as anti-inflammatory and antibacterial effects [ 28 ]. In recent years, it has been widely used in bone and soft tissue reconstruction surgery, plastic surgery, diabetic foot refractory ulcers, and chronic skin ulcers [ 29 ].…”

Section: Discussionmentioning

confidence: 99%

Effect and Safety Analysis of PRP and Yifu Combined with Ultrapulsed CO2 Lattice Laser in Patients with Sunken Acne Scar

Wang

Wang²,

Zhang

et al. 2022

Journal of Healthcare Engineering

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Objective. To investigate the effect and safety of PRP and Yifu combined with ultrapulsed CO2 lattice laser in patients with sunken acne scar. Methods. 700 subjects were selected from the group of patients with sunken acne scar treated in our hospital from November 2010 to December 2020. They were divided into control group (n = 350) and study group (n = 350). The grouping was mainly based on the random number table method. Patients in the control group were treated with ultrapulse CO2 lattice laser, while those in the study group were treated with ultrapulse CO2 lattice laser combined with PRP and Yifu. The clinical effect, scar improvement and quality of life before and after treatment, and adverse events during treatment were compared between the two groups. The clinical effect was categorized into cure after treatment, significant effect, effective, and ineffective. The total effective rate = 1 − ineffective rate. Results. After treatment, the total effective rate of the study group (81.43%) was higher than that of the control group (70.00%). After treatment, ECCA, VSS scores, daily activities, symptoms and feelings, work and study, leisure and entertainment, interpersonal relationship, treatment status, and total scores were all lower in both groups than before treatment, and the study group was lower than the control group. During the treatment, the incidence of adverse events in the study group (17.33%) was lower than that in the control group (28.57%), P < 0.05 . Conclusion. PRP and Yifu combined with ultrapulse CO2 lattice laser in the treatment of sunken acne scar can effectively improve the scar, reduce the incidence of adverse events, and the treatment effect is obvious, which can improve the quality of life of the patients.

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Section: Discussionmentioning

confidence: 99%

Effect and Safety Analysis of PRP and Yifu Combined with Ultrapulsed CO2 Lattice Laser in Patients with Sunken Acne Scar

Wang

Wang²,

Zhang

et al. 2022

Journal of Healthcare Engineering

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“…The Meek micrograph technique was developed to gain the most coverage from a small amount of available skin, using small full-thickness skin grafts, and demonstrated promising results in terms of contracture rate. 88,89 Fat grafting was utilized to restore volume and counteract skin tethering as well as for its therapeutic effects 35,90–96…”

Section: Resultsmentioning

confidence: 99%

“…The Meek micrograph technique was developed to gain the most coverage from a small amount of available skin, using small fullthickness skin grafts, and demonstrated promising results in terms of contracture rate. 88,89 Fat grafting was utilized to restore volume and counteract skin tethering as well as for its therapeutic effects 35,[90][91][92][93][94][95][96] Engineered substances provided excellent options for coverage and improved contracture rates, especially in the setting of extensive burns (Supplemental Digital Content 9, http://links.lww.com/PRSGO/C986). Dermal matrices were frequently used (n = 29).…”

Section: Overview Of Techniquesmentioning

confidence: 99%

Prevention and Treatment of Burn Scar Contracture: A Practical Review

Raborn,

Janis

2024

Plastic and Reconstructive Surgery - Global Open

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Summary: Burn contracture affects close to one-third of all burn patients, leading to significant functional impairment and costs. Effective prevention and treatment strategies are necessary to decrease morbidity and unnecessary costs. This scoping review aimed to summarize prevention and treatment strategies used for management of burn scar contractures published in the literature since 2000. A comprehensive PubMed review was performed in October 2022 to identify methods of burn contracture prevention and treatments. Non-English, duplicate, and unavailable articles were excluded. Data were extracted including publication year, techniques, and outcomes. A total of 327 publications met criteria for inclusion. Most articles were published in 2011 (n = 22). Treatment strategies were discussed in 82.9% of studies, prevention in 16.5%, and both in 0.6%. The most common areas discussed included the upper extremity (n = 127) and neck (n = 102). Flaps were the most frequently used method (n = 208), followed by autografts (n = 89). Most preventative therapies were still in early stages of development. Burn contracture management requires a highly individualized approach with many available reconstructive techniques available. Further research is needed to improve prevention techniques and decrease morbidity and cost to patients.

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“…Haney et al used ADM in genitourinary reconstructive surgery, which is a new approach for ADM [ 38 ]. ADM is also used in burn treatments [ 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 ].…”

Section: Discussionmentioning

confidence: 99%

Co-Graft of Acellular Dermal Matrix and Split Thickness Skin Graft—A New Reconstructive Surgical Method in the Treatment of Hidradenitis Suppurativa

et al. 2022

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Hidradenitis suppurativa is a chronic disease that significantly reduces patients’ quality of life. Patients are chronically treated with systemic therapies, which are often ineffective. Surgical treatment for severe cases of hidradenitis suppurativa is one option for affected patients. Surgical treatment has its limitations, and wound closure may be particularly problematic. This requires the use of reconstructive techniques. The methods of choice for wound closure are split-thickness skin grafts or local flaps reconstructions. However, each method has its limitations. This is a presentation of a new reconstructive surgical method in hidradenitis suppurativa surgery: the use of a co-graft of Acellular dermal matrix and split thickness skin graft as a novel method in wound closure after wide excisions, based on two cases. The results of this method are very promising: we achieved very fast wound closure with good aesthetic results regarding scar formation. In this paper, we used several examinations: laser speckle analysis, cutometer tests, and health-related quality of life (QoL) questionnaire to check the clinical impact of this method. Our initial results are very encouraging. ADM with STSG as a co-graft could be widely used in reconstructive surgery. This is a preliminary study, which should be continued in further, extended research.

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Recent strategic approach in postburn extremity scars and contractures

Cited by 5 publications

References 50 publications

Effect and Safety Analysis of PRP and Yifu Combined with Ultrapulsed CO2 Lattice Laser in Patients with Sunken Acne Scar

Effect and Safety Analysis of PRP and Yifu Combined with Ultrapulsed CO2 Lattice Laser in Patients with Sunken Acne Scar

Prevention and Treatment of Burn Scar Contracture: A Practical Review

Co-Graft of Acellular Dermal Matrix and Split Thickness Skin Graft—A New Reconstructive Surgical Method in the Treatment of Hidradenitis Suppurativa

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