Recent trends in biodegradable polyester nanomaterials for cancer therapy

Gupta, Piyush Kumar; Gahtori, Rekha; Govarthanan, Kavitha; Sharma, Vineeta; Pappuru, Sreenath; Pandit, Soumya; Mathuriya, Abhilasha Singh; Dholpuria, Sunny; Bishi, Dillip Kumar

doi:10.1016/j.msec.2021.112198

Cited by 47 publications

(24 citation statements)

References 98 publications

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“…22 PLA is produced from lactic acid via starch fermentation of lactic bacteria, 10 which gained attention due to its availability, cheapness, 23 biodegradability, and biocompatibility. 21,24 PLA is used mainly for general packaging applications, thanks to its processability through common thermoplastic technologies. 21 Furthermore, PLA nanomaterial has been used extensively for numerous biomedical applications, for example, drug delivery, nanocarriers to encapsulate water-insoluble drugs in the circulating blood, and so on.…”

Section: Polyestersmentioning

confidence: 99%

“…21 Furthermore, PLA nanomaterial has been used extensively for numerous biomedical applications, for example, drug delivery, nanocarriers to encapsulate water-insoluble drugs in the circulating blood, and so on. 24 Regarding biodegradation, several studies showed that PLA is completely degraded under compost conditions. 10 PHA is another material applied in many sectors, which is a polyester of various hydroxy alkanoates that is synthesized by microbial fermentation.…”

Section: Polyestersmentioning

confidence: 99%

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Biodegradable polymers: A review about biodegradation and its implications and applications

2022

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Plastic waste pollution is a global environmental problem that could be solved by biodegradable materials. In addition, its biodegradability has been important for medical applications. In this way, the biodegradability performance has been investigated for different materials under diversified environmental conditions. In this context, this review shows the main up-to-date biodegradable polymers (from renewable sources and fossil-based), their structure and properties, and their biodegradability characteristics. Also, this review shows the effect of polymer properties and environmental conditions on biodegradability, methods of biodegradability and toxicity determination, modification processes to enhance biodegradability, and main applications of biodegradable polymers for agriculture, medical, and packaging. Finally, this review presents a discussion of the implications of biodegradation on the environment, the current context, and future perspectives of plastic biodegradation.

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Section: Polyestersmentioning

confidence: 99%

Section: Polyestersmentioning

confidence: 99%

Biodegradable polymers: A review about biodegradation and its implications and applications

2022

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“…All these features can ensure that MOFs can be more efficiently carried for different therapeutic molecules or drugs. Although the metal-free polymeric or liposomal nanocarriers have better stability and biocompatibility ( Gupta et al, 2021 ; Liang et al, 2022 ). Inorganic metals such as Zn, Ti, Fe, Mg, Cu, Zr, and Co. contained by MOFs are not only essential elements for body, but also participating in important life activities such as cell proliferation, differentiation, and metabolism.…”

Section: Classification Of Mnpsmentioning

confidence: 99%

Metal-based nano-delivery platform for treating bone disease and regeneration

Liu

Xu²,

Qiao³

et al. 2022

Front. Chem.

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Owing to their excellent characteristics, such as large specific surface area, favorable biosafety, and versatile application, nanomaterials have attracted significant attention in biomedical applications. Among them, metal-based nanomaterials containing various metal elements exhibit significant bone tissue regeneration potential, unique antibacterial properties, and advanced drug delivery functions, thus becoming crucial development platforms for bone tissue engineering and drug therapy for orthopedic diseases. Herein, metal-based drug-loaded nanomaterial platforms are classified and introduced, and the achievable drug-loading methods are comprehensively generalized. Furthermore, their applications in bone tissue engineering, osteoarthritis, orthopedic implant infection, bone tumor, and joint lubrication are reviewed in detail. Finally, the merits and demerits of the current metal-based drug-loaded nanomaterial platforms are critically discussed, and the challenges faced to realize their future applications are summarized.

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“…In recent years, poly(propylene carbonate) (PPC) as a sustainable and environmentally friendly polymer has attracted the general interest of researchers since it utilizes CO 2 avoiding its disposal. − The large-scale use of PPC can realize the recycling of CO 2 , as well as relieve the shortage of nonrenewable (petroleum) resources. More importantly, PPC can improve environmental pollution caused by nondegradable plastics as a biodegradable material. , PPC features good transparency, excellent gas barrier properties, thermal shape memory, good biocompatibility, and processability. However, some inherent defects of PPC, such as a lower glass transition temperature, weak thermal stability, and poor mechanical strength, greatly limit its wide application. − Therefore, it is of great significance to improve the defects of PPC to achieve excellent comprehensive performances and broaden its application field for the sustainable development of the environment and human beings.…”

Section: Introductionmentioning

confidence: 99%

“…More importantly, PPC can improve environmental pollution caused by nondegradable plastics as a biodegradable material. 4,5 PPC features good transparency, excellent gas barrier properties, thermal shape memory, good biocompatibility, and processability. However, some inherent defects of PPC, such as a lower glass transition temperature, weak thermal stability, and poor mechanical strength, greatly limit its wide application.…”

Section: ■ Introductionmentioning

confidence: 99%

CO₂-Based Poly(propylene carbonate) Functionalized for Sustainable Nanocomposites by a Controllable Magnetic Field

Liang

et al. 2022

ACS Sustainable Chem. Eng.

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To alleviate environmental problems caused by carbon emissions, the modified application of the CO 2 -based polymer has attracted extensive scientific and technological interest. In this study, a series of sustainable nanocomposites were fabricated by a magnetic field with controllable direction to achieve nanofiller orientation in the CO 2 -derived poly(propylene carbonate) (PPC) matrix, and magnetic graphene nanosheets (FG) with varying magnetization were synthesized through a simple coprecipitation process using graphene oxide and iron-containing salts. The resultant nanocomposites not only exhibited anisotropic mechanical properties but also presented anisotropic thermal conductivity (TC) and electromagnetic interference (EMI) shielding properties in different magnetic field directions. The nanocomposites with a parallel orientation showed further significant improvements compared with the vertically oriented nanocomposites in terms of the mechanical properties, in-plane TC, and EMI shielding performances at the same FG loading. This was possibly attributed to the more regular arrangement of the two-dimensional FG nanosheets in the horizontal magnetic field. In addition, these nanocomposites showed a rapid magnetic response when the magnets were in close proximity. This study on PPC/FG nanocomposites with a controllable orientation structure and magnetic response could provide new ideas for the development of applications of CO 2 -based PPC materials in the functional and intelligent material field.

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Recent trends in biodegradable polyester nanomaterials for cancer therapy

Cited by 47 publications

References 98 publications

Biodegradable polymers: A review about biodegradation and its implications and applications

Biodegradable polymers: A review about biodegradation and its implications and applications

Metal-based nano-delivery platform for treating bone disease and regeneration

CO₂-Based Poly(propylene carbonate) Functionalized for Sustainable Nanocomposites by a Controllable Magnetic Field

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Recent trends in biodegradable polyester nanomaterials for cancer therapy

Cited by 47 publications

References 98 publications

Biodegradable polymers: A review about biodegradation and its implications and applications

Biodegradable polymers: A review about biodegradation and its implications and applications

Metal-based nano-delivery platform for treating bone disease and regeneration

CO2-Based Poly(propylene carbonate) Functionalized for Sustainable Nanocomposites by a Controllable Magnetic Field

Contact Info

Product

Resources

About

CO₂-Based Poly(propylene carbonate) Functionalized for Sustainable Nanocomposites by a Controllable Magnetic Field