Recent trends on biomaterials for tissue regeneration applications: review

Abstract

Tissue engineering is approach of replacing or regeneration of biological functions of tissues or organs by using combination of biomaterials, biomolecules and cells. Tissue engineering mainly depends scaffold biomaterials and scaffold fabrication methods. Therefore, there have been progressive investigation and development of new biomaterials with different formulations to help and achieve necessary requirements in the tissue engineering applications. This review is briefly representing necessary features associated with biomaterial type and design required for tissue regeneration applications, and presenting earlier research in tissue engineering field and new trends for future implementation. It is mainly focusing on generations of biomaterials and discovery tissue engineering field. As well as, different types of biomaterials, such as bioceramics, bioactive glasses, synthetic and natural polymers and their derived composites, used in fabrication of scaffolds (as a main part of tissue engineering) are demonstrated in this review. Scaffold fabrication methods are also reviewed here. Moreover, it is showing the recent achievements in tissue engineering field for bone, skin, cartilage, neural, and cardiac regeneration as a pre-clinical procedure for repair of injured and diseased tissues and organs. Finally, recent trends and challenges of biomaterials for tissue regeneration are presented also in this review. Graphical abstract

Advancements in application of chitosan and cyclodextrins in biomedicine and pharmaceutics: recent progress and future trends

“…The resulting composite nanobers displayed a smooth, uniform structure with hydrophobic properties. [57][58][59][60][61][62][63][64][65][66][67][68] Additionally, the presence of starch and chitosan promoted L929 cell migration, aiding in wound healing. Overall, these nanobers have the potential to eliminate pathogens and enhance wound healing.…”

Biomaterials evolution: from inert to instructive

“…Additionally, they release pharmacological substances that promote or inhibit specific cellular activities. 19 This enables them to stimulate cellular responses at the molecular level, leading to improved tissue regeneration. The latest advancement in biomaterials research is the development of fourth-generation biomaterials, also known as bioelectronics materials.…”

Fabrication and Characterization of a Bioscaffold Using Hydroxyapatite and Unsaturated Polyester Resin

“…The materials that originate from living things or utilized in body-related treatments have been referred to as “biomaterials” in different contexts. − The discipline of polymer research was initially founded on the application of polymers in biomaterials. , Large-scale arterial transplants, synthetic bones, hip gadgets, and other long-lasting artificial body parts all depend on polymers. , Analysis is still being done to maximize the reliability and effectiveness of those substances . The demands of polymers look more favorable and better adapted to the physiological requirements of the comparatively recent discipline of tissue science and engineering, where polymers are implemented to support the rebuilding of multifaceted organs. , A polymeric substance has to be considered “biocompatible” in order to serve as a substance in biomaterial applications.…”