2017 IEEE Biomedical Circuits and Systems Conference (BioCAS) 2017
DOI: 10.1109/biocas.2017.8325220
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Recombinase-based genetic circuit optimization

Abstract: The rapid advancements of synthetic biology show promising potential in biomedical and other applications. Recently, recombinases were proposed as a tool to engineer genetic logic circuits with long-term memory in living and even mammalian cells. The technology is under active development, and the complexity of engineered genetic circuits grows continuously. However, how to minimize a genetic circuit composed of recombinase-based logic gates remain largely open. In this paper, we formulate the problem as a cub… Show more

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