Recommendations for the integral diagnosis of chronic viral hepatitis in a single analytical extraction

Crespo, Javier; Cabezas, Joaquín; Aguilera, Antonio; Berenguer, Marina; Buti, Marı́a; Forns, Xavier; García, Féderico; García‐Samaniego, J.; Hernández‐Guerra, Manuel; Jorquera, Francisco; Lazarus, Jeffrey V.; Lens, Sabela; Martró, Elisa; Pineda, Juan A; Prieto, Martín; Rodríguez‐Frías, Francisco; Rodríguez, Manuel; Serra, Miguel; Turnés, Juan; Domínguez-Hernández, Raquel; Calleja, Jose Luis

doi:10.1016/j.gastre.2022.09.001

Cited by 2 publications

(3 citation statements)

References 100 publications

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“…The HDV reflex testing is already performed in specific hospitals or in specific regions within a limited set of countries (e.g. Spain, France, Brazil, Sweden, Canada), but not at the national level [15][16][17].…”

Section: Discussionmentioning

confidence: 99%

Hepatitis B Delta: assessment of the knowledge and practices of hepato-gastroenterologists practicing in non-academic settings in France

Cadranel,

Zougmoré,

Efole

et al. 2024

European Journal of Gastroenterology &Amp; Hepatology

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Background Data on the management of Hepatitis B-Delta (HB-D) by hepatogastroenterologists (HGs) practicing in nonacademic hospitals or private practices are unknown in France. Objective We aimed to evaluate the knowledge and practices of HGs practicing in nonacademic settings regarding HB-D. Methods A Google form document was sent to those HGs from May to September 2021. Results A total of 130 HGs (mean age, 45 years) have participated in this survey. Among HBsAg-positive patients, Delta infection was sought in only 89% of cases. Liver fibrosis was assessed using FibroScan in 77% of the cases and by liver biopsy in 81% of the cases. A treatment was proposed for patients with >F2 liver fibrosis in 49% of the cases regardless of transaminase levels and for all the patients by 39% of HGs. Responding HGs proposed a treatment using pegylated interferon in 50% of cases, bulevirtide in 45% of cases and a combination of pegylated interferon and bulevirtide in 40.5% of cases. Among the criteria to evaluate the treatment efficacy, a decrease or a normalization of transaminases was retained by 89% of responding HGs, a reduction of liver fibrosis score for 70% of them, an undetectable delta RNA and HBsAg for 55% of them and a 2 log 10 decline in delta viremia for 62% of the cases. Conclusion Hepatitis Delta screening was not systematically performed in HBsAg-positive patients despite the probable awareness and knowledge of the few responders who were able to prescribe treatments of hepatitis delta.

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Section: Discussionmentioning

confidence: 99%

Hepatitis B Delta: assessment of the knowledge and practices of hepato-gastroenterologists practicing in non-academic settings in France

Cadranel,

Zougmoré,

Efole

et al. 2024

European Journal of Gastroenterology &Amp; Hepatology

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show abstract

“…In this regard, the professional associations in Spain (the Spanish Association for the Study of the Liver, the Viral Hepatitis Study Group of the Spanish Society of Infectious Diseases and Clinical Microbiology and the Spanish Society of Digestive Pathology), a country close to eliminating HCV infection, have developed a consensus for the comprehensive diagnosis of chronic viral hepatitis (Figure 1). The main objective of this consensus is to establish a series of recommendations that allow for the complete diagnosis of chronic viral hepatitis in a single analytical extraction 6 . Likewise, via this research letter, we aim to make a series of recommendations for health professionals, services and programs, in order to prevent infections and facilitate early diagnosis, the dissemination of information on hepatitis and, finally, improvement in healthcare models, guaranteeing follow‐up and access to treatment.…”

Section: Figurementioning

confidence: 99%

“…The main objective of this consensus is to establish a series of recommendations that allow for the complete diagnosis of chronic viral hepatitis in a single analytical extraction. 6 Likewise, via this research letter, we aim to make a series of recommendations for health professionals, services and programs, in order to prevent infections and facilitate early diagnosis, the dissemination of information on hepatitis and, finally, improvement in healthcare models, guaranteeing follow-up and access to treatment.…”

Section: A Call For the Comprehensive Diagnosis Of Viral Hepatitis As...mentioning

confidence: 99%

A call for the comprehensive diagnosis of viral hepatitis as a key step towards its elimination

Crespo

Calleja

Cabezas

et al. 2023

Liver International

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Recommendations for the integral diagnosis of chronic viral hepatitis in a single analytical extraction

Cited by 2 publications

References 100 publications

Hepatitis B Delta: assessment of the knowledge and practices of hepato-gastroenterologists practicing in non-academic settings in France

Hepatitis B Delta: assessment of the knowledge and practices of hepato-gastroenterologists practicing in non-academic settings in France

A call for the comprehensive diagnosis of viral hepatitis as a key step towards its elimination

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