Recommendations for the prevention and diagnosis of asthma in children: Evidence from international guidelines adapted for Mexico

Linnemann, Désirée E.S. Larenas; Navarro, Blanca E. del Río; Luna-Pech, Jorge A.; Lombard, Jade Romero; Rosas, Jimena Villaverde; Salas, Mónica; Vega, Margarita Fernández; Martell, José Antonio Ortega; Estrada, Elena; Butrón, José Luis Mayorga; Hernández, Jorge Salas; Vázquez-García, Juan Carlos; Aldana, Ignacio; Becerra, Mario Humberto Vargas; Bedolla-Barajas, Martín; Pérez, Noel Rodríguez; Aranda, Alvaro; Gonzalez, Cássia; Bolaños, Carlos García; Galindo, Claudia Garrido; Mendoza-Hernández, David Alejandro; López, Enrique Mendoza; Pérez, Gerardo López; Gutierrez, Hector; Molina, H. León; Lanza, H. Martínez de la; Aguilar, Héctor Stone; Vera, Javier Gómez; Salinas, Jorge Olvera; Romero, José Luis Gálvez; Sáenz, José Santos Lozano; Gama, Juan Ignacio Salgado; Jiménez-Chobillón, Marcos Alejandro; Avilés, M.A. García; Balanzar, M.P. Guinto; Ávalos, Miguel Alejandro Medina; Angeles, R. Camargo; Torrentera, Rogelio García; Freyre, Saraí Toral; Narvaez, Gabriel Montes; Gómez, Héctor Solorio; Peña, Juan Rosas; Tapia, S.J. Romero; Herrera, A. Reyes; Schacht, Francisco Cuevas; Flores, Joaquín Esquer; Hazouri, José Antonio Sacre; Martínez, Lorenzo Compean; Ma, Peñalver Sanchez; Salinas, Sergio Garza; Loyola, C. Baez; Alvarado, I. Romero; Reyes, José Luis Miguel; Espinosa, L.E. Huerta; Flores, Manuel Ángel Correa; Martínez, Ricardo Castro

doi:10.1016/j.aller.2017.05.011

Cited by 2 publications

(1 citation statement)

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“…Breastfeeding is advised for reasons other than preventing asthma [12 & ]. After a review of available guidelines, Linneman et al [13] concluded that there is no need to exclude allergens from the maternal diet for asthma prevention. Further, observational studies in early life suggest that a Mediterranean style diet in younger children is associated with a lower prevalence of asthma [6].…”

Section: Introductionmentioning

confidence: 99%

Dietary strategies for the prevention of asthma in children

Venter

Smith

Arshad

2021

Current Opinion in Allergy &Amp; Clinical Immunology

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Purpose of reviewThis review summarizes information relating to dietary intake during pregnancy, lactation and early life that may prevent childhood asthma. This review also summarizes how future studies may be improved. Recent findingsRecent findings from observational studies suggest that eating according to certain dietary patterns during pregnancy, such as the dietary inflammatory index, Mediterranean diet and Maternal diet index, may reduce asthma and or wheeze in the child. Vitamin D supplementation with higher doses than recommended during pregnancy may be associated with reduced early transient childhood wheezing in the offspring. Higher levels of omega-3 fatty acids in breast milk may be protective against childhood asthma. Breastfeeding infants has been shown to offer many benefits to mother and child but a direct relationship between breastfeeding and the development of asthma has not been established. During childhood, infants and children may need to reduce their intake of advanced glycation end products, increase their food intake according to the traditional Mediterranean diet and increase the diversity of foods eaten.

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Section: Introductionmentioning

confidence: 99%

Dietary strategies for the prevention of asthma in children

Venter

Smith

Arshad

2021

Current Opinion in Allergy &Amp; Clinical Immunology

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Astragalus Oral Solution Ameliorates Allergic Asthma in Children by Regulating Relative Contents of CD4+CD25highCD127low Treg Cells

2018

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Objective: To explore the effects of Astragalus oral solution (AOS) on allergic asthma in children by investigating relative contents of CD4+CD25highCD127low Treg cells.Methods: The contents of Astragaloside A in AOS were detected by using HPLC. Eighty children with allergic asthma were recruited from February 2016 to June 2017, and randomly assigned into the control group (received placebo, 0.1% quinine chloride in deionized water, daily) and the AOS group (received 10 mL AOS daily). After 6-month treatment, therapeutic results were compared between the two groups. Serum levels of IL-10 and TGF-beta, Th1 cytokines (IL-2 and IFN-γ), and Th2 cytokines (IL-4 and IL-6) were measured by using ELISA kits. Relative contents of CD4+CD25highCD127low Treg cells were determined by using flow cytometry.Results: Astragaloside A was the main ingredient of AOS with 0.216 ± 0.027 mg/mL from six-batch samples. After 6-month therapy, the AOS group showed improved forced expiratory volume in 1 s (FEV1) and the Pediatric Asthma Quality of Life Questionnaire (PAQLQ) scores compared with the control group (P < 0.05). Serum level of IL-10 was higher and the levels of TGF-beta, Th1 cytokines (IL-2 and IFN-γ), and Th2 cytokines (IL-4 and IL-6) were lower in the AOS group than in the control group (P < 0.05). AOS treatment increased the percentage of gated CD4+ T cells, CD4+CD25+ T cells, CD4+CD25high Treg cells, CD4+CD25+FoxP3+ Treg cells and CD4+CD25highCD127low Treg cells when compared with the control group (P < 0.05).Conclusions: Astragaloside A was the main component of AOS, and AOS ameliorated allergic asthma in children by regulating relative contents of CD4+CD25highCD127low Treg cells.

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Recommendations for the prevention and diagnosis of asthma in children: Evidence from international guidelines adapted for Mexico

Abstract: For the prevention and diagnosis sections, applying the AGREE-II method is useful to develop a scientifically-sustained document, adjusted to the local reality per country, as is the Mexican Guideline on Asthma.

Cited by 2 publications

References 4 publications

Dietary strategies for the prevention of asthma in children

Dietary strategies for the prevention of asthma in children

Astragalus Oral Solution Ameliorates Allergic Asthma in Children by Regulating Relative Contents of CD4+CD25highCD127low Treg Cells

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