Recommendations from a Portuguese Expert Group for Discontinuation of Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia Patients in Clinical Practice
Abstract:Until recently, the main goal of chronic myeloid leukemia therapy was disease control with the best overall survival, which required lifelong treatment. However, currently, the treatment-free remission concept is becoming an important goal in clinical practice, and several tyrosine kinase inhibitors discontinuation studies have shown that round 50% of patients with a durable deep molecular response beyond major molecular response successfully interrupt tyrosine kinase inhibitors for at least three years witho… Show more
“…In this sense, several international guidelines have established the criteria for the implementation of TFR in CML patients that can be used in the clinical practice. 24 , 25 , 26 , 27 , 28 , 29 …”
“…In this sense, several international guidelines have established the criteria for the implementation of TFR in CML patients that can be used in the clinical practice. 24 , 25 , 26 , 27 , 28 , 29 …”
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