Reconstruction of in vivo flow velocity fields based on a rapid ultrasound image segmentation and B-spline regularization framework

Gronli, Thomas; Smistad, Erik; Nyrnes, Siri Ann; Gómez, Alberto; Løvstakken, Lasse

doi:10.1109/ultsym.2016.7728867

Cited by 2 publications

(4 citation statements)

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“…This reconstruction can only be trusted when reliable tissue border information can be obtained, and limited out-of-plane flow is present. 24 Contrary to VFM, the wall information is only optional. Different vortex parameters have been proposed for flow analysis.…”

Section: Discussionmentioning

confidence: 99%

“…performed the echocardiographic examinations, occasionally together with the engineers developing the technique. In total, 102 subjects were included: 51 normal control subjects (ranging in age from 2-day-old term neonates to 10-yearold children), 47 cardiac patients (age range, 1 day to 11.5 years), and four healthy fetuses (21,24,29, and 29 weeks of age).…”

Section: Patient Selectionmentioning

confidence: 99%

“…Previous validation of BST in technical publications is summarized in Supplemental Table 1. 1,2,20,[23][24][25] In this work, we further validated pediatric BST on the basis of images obtained with a 6 MHz phasedarray probe and using an in-house-made rotating tissue-mimicking phantom with a known velocity profile. The phantom had a constant angular velocity (285 rounds/min), resulting in a span of velocities within the phantom between 0 m/sec at the center and 1.5 m/sec at the edges.…”

Section: Accuracy Of the Velocity Estimates In Vitro And In Vivomentioning

confidence: 99%

“…However, valid estimates are seen down to 8 cm in depth. For dropout regions due to wall filtering, velocity fields can optionally be reconstructed by including wall motion information, 24 similar to that used in VFM, as shown on the right in Figure 5. In this example, a lateral vortex above the mitral valve is better displayed (Figure 5, Supplemental Video 1 available at www.onlinejase.com).…”

Section: Bst Feasibility Accuracy and Tq In Vivomentioning

confidence: 99%

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Blood Speckle-Tracking Based on High–Frame Rate Ultrasound Imaging in Pediatric Cardiology

Nyrnes

Fadnes

Wigen

et al. 2020

Journal of the American Society of Echocardiography

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Background: Flow properties play an important role in cardiac function, remodeling, and morphogenesis but cannot be displayed in detail with today's echocardiographic techniques. The authors hypothesized that blood speckle-tracking (BST) could visualize and quantify flow patterns. The aim of this study was to determine the feasibility, accuracy, and potential clinical applications of BST in pediatric cardiology.Methods: BST is based on high-frame rate ultrasound, using a combination of plane-wave imaging and parallel receive beamforming. Pattern-matching techniques are used to quantify blood speckle motion. Accuracy of BST velocity measurements was validated using a rotating phantom and by comparing BST-derived inflow velocities with pulsed-wave Doppler obtained in the left ventricles of healthy control subjects. To test clinical feasibility, 102 subjects (21 weeks to 11.5 years of age) were prospectively enrolled, including healthy fetuses (n = 4), healthy control subjects (n = 51), and patients with different cardiac diseases (n = 47). Results:The phantom data showed a good correlation (r = 0.95, with a tracking quality threshold of 0.4) between estimated BST velocities and reference velocities down to a depth of 8 cm. There was a good correlation (r = 0.76) between left ventricular inflow velocity measured using BST and pulsed-wave Doppler. BST displayed lower velocities (mean 6 SD, 0.59 6 0.14 vs 0.82 6 0.21 m/sec for pulsed-wave Doppler). However, the velocity amplitude in BST increases with reduced smoothing. The clinical feasibility of BST was high, as flow patterns in the area of interest could be visualized in all but one case (>99%).Conclusions: BST is highly feasible in fetal and pediatric echocardiography and provides a novel approach for visualizing blood flow patterns. BST provides accurate velocity measurements down to 8 cm, but compared with pulsed-wave Doppler, BST displays lower velocities. Studying blood flow properties may provide novel insights into the pathophysiology of pediatric heart disease and could become an important diagnostic tool. (J

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Section: Discussionmentioning

confidence: 99%

Section: Patient Selectionmentioning

confidence: 99%

Section: Accuracy Of the Velocity Estimates In Vitro And In Vivomentioning

confidence: 99%

Section: Bst Feasibility Accuracy and Tq In Vivomentioning

confidence: 99%

See 2 more Smart Citations

Blood Speckle-Tracking Based on High–Frame Rate Ultrasound Imaging in Pediatric Cardiology

Nyrnes

Fadnes

Wigen

et al. 2020

Journal of the American Society of Echocardiography

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4-D Intracardiac Ultrasound Vector Flow Imaging–Feasibility and Comparison to Phase-Contrast MRI

Wigen¹,

Fadnes²,

Rodríguez-Molares³

et al. 2018

IEEE Trans. Med. Imaging

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In vivo characterization of intracardiac blood velocity vector fields may provide new clinical information but is currently not available for bedside evaluation. In this paper, 4-D vector flow imaging for intracardiac flow assessment is demonstrated using a clinical ultrasound (US) system and a matrix array transducer, without the use of contrast agent. Two acquisition schemes were developed, one for full volumetric coverage of the left ventricle (LA) at 50 vps and a 3-D thick-slice setup with continuous frame acquisition (4000 vps), both utilizing ECG-gating. The 3-D vector velocity estimates were obtained using a novel method combining phase and envelope information. In vitro validation in a rotating tissue-mimicking phantom revealed velocity estimates in compliance with the ground truth, with a linear regression slope of 0.80, 0.77, and 1.03 for the , , and velocity components, and with standard deviations of 2.53, 3.19, and 0.95 cm/s, respectively. In vivo measurements in a healthy LV showed good agreement with PC-MRI. Quantitative analysis of energy loss (EL) and kinetic energy (KE) further showed similar trends, with peak KE at 1.5 and 2.4 mJ during systole and 3.6 and 3.1 mJ for diastole for US and PC-MRI. Similar for EL, 0.15- 0.2 and 0.7 mW was found during systole and 0.6 and 0.7 mW during diastole, for US and PC-MRI, respectively. Overall, a potential for US as a future modality for 4D cardiac vector flow imaging was demonstrated, which will be further evaluated in clinical studies.

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Reconstruction of in vivo flow velocity fields based on a rapid ultrasound image segmentation and B-spline regularization framework

Cited by 2 publications

References 4 publications

Blood Speckle-Tracking Based on High–Frame Rate Ultrasound Imaging in Pediatric Cardiology

Blood Speckle-Tracking Based on High–Frame Rate Ultrasound Imaging in Pediatric Cardiology

4-D Intracardiac Ultrasound Vector Flow Imaging–Feasibility and Comparison to Phase-Contrast MRI

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